TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay without pre-incubationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 0.5nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay without pre-incubationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 0.700nMAssay Description:Inhibition of human BTK in human microglia cellsMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: <1nMAssay Description:Inhibition of human JAK3 using Biotin-Lyn-Substrate-2 in presence of 1 mM ATP by phosphotyrosine-specific ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay without pre-incubationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 2nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay without pre-incubationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human JAK1 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 4nMAssay Description:Inhibition of human JAK1 using Biotin-Lyn-Substrate-2 in presence of 1 mM ATP by phosphotyrosine-specific ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human JAK2 using Biotin-Lyn-Substrate-2 in presence of 1 mM ATP by phosphotyrosine-specific ELISAMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of human Tyk2 using Biotin-Lyn-Substrate-2 in presence of 1 mM ATP by phosphotyrosine-specific ELISAMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 5.10nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay with pre-incubationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human JAK1 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 23nMAssay Description:Inhibition of recombinant human Tyk2 expressed in sf21 baculovirus expression system assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of recombinant human Tyk2 expressed in sf21 baculovirus expression system assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human JAK3 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of recombinant human JAK2 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 33nMAssay Description:Inhibition of BTK (unknown origin) One-hour enzymatic assay without pre-incubationMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 77nMAssay Description:Inhibition of recombinant human JAK2 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 636nMAssay Description:Inhibition of recombinant human JAK1 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 992nMAssay Description:Inhibition of recombinant human JAK3 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human JAK2 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human Tyk2 expressed in sf21 baculovirus expression system assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: 6.49E+3nMAssay Description:Inhibition of recombinant human JAK3 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human Tyk2 expressed in sf21 baculovirus expression system assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human JAK3 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human JAK2 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Roche Innovation Center Shanghai
Curated by ChEMBL
Roche Innovation Center Shanghai
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of recombinant human JAK1 assessed as phosphorylation level in presence of 1 mM ATPMore data for this Ligand-Target Pair