Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50018510
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50538083(CHEMBL4638292)
Affinity DataIC50: 6nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50: 6nMAssay Description:Inhibition of human wild type DYRK1A (M1 to S629) expressed in bacterial system by Ambit Kinomescan binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50: 6nMAssay Description:Inhibition of human DYRK1A at 3 uM in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50375654(CHEMBL99203 | US11633415, Compound 5-iodotubercidi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of DYRK1A (unknown origin) in presence of ATP at 15 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50538083(CHEMBL4638292)
Affinity DataIC50: 16nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 27nMAssay Description:Inhibition of DYRK1A (unknown origin) at 10 uM by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50597836(CHEMBL5186778)
Affinity DataIC50: 40nMAssay Description:Inhibition of human GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50538085(CHEMBL4634969)
Affinity DataIC50: 43nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50466137(CHEMBL4280328 | US11547712, Compound 3-15)
Affinity DataKd:  71nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant at 3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50571728(CHEMBL4855547)
Affinity DataIC50: 89nMAssay Description:Inhibition of human DYRK1A by Eu kinase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM100152(cid_5359389 | SMR001233259 | HARMINE | 7-methoxy-1...)
Affinity DataIC50: 100nMAssay Description:Inhibition of DYRK1A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50538083(CHEMBL4638292)
Affinity DataIC50: 100nMAssay Description:Inhibition of human wild type DYRK1A (M1 to S629) expressed in bacterial system by Ambit Kinomescan binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50466136(CHEMBL4292463 | US11547712, Compound 3-12)
Affinity DataKd:  185nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant at 3 uMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50466133(CHEMBL4292847 | US11547712, Compound 3-1)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50466133(CHEMBL4292847 | US11547712, Compound 3-1)
Affinity DataKd:  7.30E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as dissociation constant by ADP hunter plus assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50367664(CHEMBL4066450)
Affinity DataIC50: 8.30E+3nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Human)
Icahn School of Medicine At Mount Sinai

Curated by ChEMBL
LigandPNGBDBM50466133(CHEMBL4292847 | US11547712, Compound 3-1)
Affinity DataIC50: 9.41E+3nMAssay Description:Inhibition of DYRK1A (unknown origin) at 1 uM by kinomescan methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/20/2024
Entry Details
PubMed