Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50013921
TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570884(CHEMBL4860669)
Affinity DataIC50: 1.60E+3nMAssay Description:Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570885(CHEMBL4855690)
Affinity DataIC50: 1.30E+4nMAssay Description:Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetProtein cereblon(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570886(CHEMBL4869528)
Affinity DataIC50: 2.07E+4nMAssay Description:Binding affinity to Cereblon in human Flp293T cells transfected with BRD4(BD2)-GFP fusion protein and mCherry reporter assessed as inhibition of dBET...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570883(CHEMBL4848695)
Affinity DataIC50: 5.68E+4nMAssay Description:Displacement of KKQYDREFLLDFQFK-FITCH from recombinant GST-tagged human eIF4E expressed in Escherichia coli BL21 (DE3) cells by fluorescence polariza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed
TargetEukaryotic translation initiation factor 4E(Human)
Dana-Farber Cancer Institute

Curated by ChEMBL
LigandPNGBDBM50570882(CHEMBL3310358)
Affinity DataIC50: 6.75E+4nMAssay Description:Displacement of KKQYDREFLLDFQFK-FITCH from recombinant GST-tagged human eIF4E expressed in Escherichia coli BL21 (DE3) cells by fluorescence polariza...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/20/2022
Entry Details Article
PubMed