Compile Data Set for Download or QSAR
Report error Found 71 Enz. Inhib. hit(s) with all data for entry = 50015503
LigandChemical structure of BindingDB Monomer ID 50587085BDBM50587085(CHEMBL5092179)
Affinity DataIC50: 0.280nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587092BDBM50587092(CHEMBL5087554)
Affinity DataIC50: 1.5nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587087BDBM50587087(CHEMBL5070268)
Affinity DataIC50: 2nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587095BDBM50587095(CHEMBL5084339)
Affinity DataIC50: 3nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -80 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587095BDBM50587095(CHEMBL5084339)
Affinity DataIC50: 5nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -80 mV holding potential incu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587092BDBM50587092(CHEMBL5087554)
Affinity DataIC50: 5.70nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587086BDBM50587086(CHEMBL5076977)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587087BDBM50587087(CHEMBL5070268)
Affinity DataIC50: 6nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50516336BDBM50516336(CHEMBL4465982)
Affinity DataIC50: 11nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587096BDBM50587096(CHEMBL5086388)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587086BDBM50587086(CHEMBL5076977)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50516336BDBM50516336(CHEMBL4465982)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587088BDBM50587088(CHEMBL5082749)
Affinity DataIC50: 30nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587092BDBM50587092(CHEMBL5087554)
Affinity DataIC50: 38nMAssay Description:Antagonist activity at rat alpha3beta4 nAChRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataKd:  44nMAssay Description:Binding affinity to rat alpha7 nAChRs assessed as dissociation constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587093BDBM50587093(CHEMBL5093476)
Affinity DataIC50: 58nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50445329BDBM50445329(CHEMBL3104242)
Affinity DataIC50: 69nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -100 mV holding potential inc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587085BDBM50587085(CHEMBL5092179)
Affinity DataIC50: 76nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587094BDBM50587094(CHEMBL5083247)
Affinity DataIC50: 86nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 97nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587090BDBM50587090(CHEMBL5076602)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587091BDBM50587091(CHEMBL5079512)
Affinity DataIC50: 200nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587084BDBM50587084(CHEMBL5074410)
Affinity DataIC50: 440nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587082BDBM50587082(CHEMBL5076584)
Affinity DataIC50: 470nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587089BDBM50587089(CHEMBL5089119)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587093BDBM50587093(CHEMBL5093476)
Affinity DataIC50: 1.20E+3nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 1.41E+3nMAssay Description:Antagonist activity at rat alpha6/alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding po...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587082BDBM50587082(CHEMBL5076584)
Affinity DataIC50: 1.56E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 1.57E+3nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587081BDBM50587081(CHEMBL5087526)
Affinity DataIC50: 1.76E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587083BDBM50587083(CHEMBL5077936)
Affinity DataIC50: 1.81E+3nMAssay Description:Antagonist activity at rat alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587083BDBM50587083(CHEMBL5077936)
Affinity DataIC50: 4.63E+3nMAssay Description:Antagonist activity at rat alpha3beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587089BDBM50587089(CHEMBL5089119)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587091BDBM50587091(CHEMBL5079512)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human alpha7 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential pr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587089BDBM50587089(CHEMBL5089119)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha3beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587081BDBM50587081(CHEMBL5087526)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587083BDBM50587083(CHEMBL5077936)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587082BDBM50587082(CHEMBL5076584)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587081BDBM50587081(CHEMBL5087526)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587089BDBM50587089(CHEMBL5089119)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta2 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587082BDBM50587082(CHEMBL5076584)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587089BDBM50587089(CHEMBL5089119)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
LigandChemical structure of BindingDB Monomer ID 50587083BDBM50587083(CHEMBL5077936)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha4beta4 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potential...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587080BDBM50587080(CHEMBL5081410)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587081BDBM50587081(CHEMBL5087526)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587083BDBM50587083(CHEMBL5077936)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetNicotinic acetylcholine receptor alpha9/alpha10(Rat)
Hainan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587082BDBM50587082(CHEMBL5076584)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at rat alpha9alpha10 nAChR expressed in xenopus oocytes assessed as inhibition of Ach- induced response at -70 mV holding potenti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
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