Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50014999
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581791BDBM50581791(CHEMBL5073221)
Affinity DataKi:  0.0320nMAssay Description:Inhibition of wild type HIV-1 protease assessed as initial inhibition constant by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCathepsin E(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581791BDBM50581791(CHEMBL5073221)
Affinity DataKi:  440nMAssay Description:Inhibition of human cathepsin E assessed as inhibition constant using ACC-GKPILFFRILK-(DNP)-(dR)-NH2 as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetCathepsin D(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581791BDBM50581791(CHEMBL5073221)
Affinity DataKi:  620nMAssay Description:Inhibition of human cathepsin D assessed as inhibition constant using ACC-GKPILFFRILK-(DNP)-(dR)-NH2 as substrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed
TargetRenin(Human)
Institute of Organic Chemistry and Biochemistry of The Czech Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50581791BDBM50581791(CHEMBL5073221)
Affinity DataKi:  1.90E+4nMAssay Description:Inhibition of human renin assessed as inhibition constant using H-R-E(EDANS)-1HPFHLVIHT-K(DABCYL)-R-OH as susbtrate by spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/5/2023
Entry Details Article
PubMed