Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50014665
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 22416BDBM22416(PAROXETINE | CHEMBL490 | (3S,4R)-3-[(1,3-benzodiox...)
Affinity DataKi:  0.0800nMAssay Description:Displacement of [125I]RTI55 binding from human wild type SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578580BDBM50578580(CHEMBL4848081)
Affinity DataKi:  1.10nMAssay Description:Displacement of [125I]RTI55 binding from human wild type SERTMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578573BDBM50578573(CHEMBL4869180)
Affinity DataKi:  5nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578564BDBM50578564(CHEMBL4853402)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578556BDBM50578556(CHEMBL4868210)
Affinity DataKi:  14nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578576BDBM50578576(CHEMBL4857489)
Affinity DataIC50: 15nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578561BDBM50578561(CHEMBL4850522)
Affinity DataKi:  15nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578552BDBM50578552(CHEMBL4853473)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578563BDBM50578563(CHEMBL4877693)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578570BDBM50578570(CHEMBL4853132)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578554BDBM50578554(CHEMBL4848149)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578566BDBM50578566(CHEMBL4850285)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 30130BDBM30130(Prozac | cid_62857 | Fluoxetin | CHEMBL41 | CHEMBL...)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578553BDBM50578553(CHEMBL4878382)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578565BDBM50578565(CHEMBL4876238)
Affinity DataKi:  41nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578577BDBM50578577(CHEMBL4847426)
Affinity DataIC50: 43nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578555BDBM50578555(CHEMBL4851108)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578558BDBM50578558(CHEMBL4864622)
Affinity DataKi:  55nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 25870BDBM25870(CITALOPRAM HYDROBROMIDE | [3H]Escitalopram | Escit...)
Affinity DataIC50: 59nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578560BDBM50578560(CHEMBL4848304)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578572BDBM50578572(CHEMBL4878448)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578557BDBM50578557(CHEMBL4863405)
Affinity DataKi:  66nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578578BDBM50578578(CHEMBL4851558)
Affinity DataIC50: 135nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578562BDBM50578562(CHEMBL4874276)
Affinity DataKi:  137nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578571BDBM50578571(CHEMBL4873814)
Affinity DataKi:  202nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578567BDBM50578567(CHEMBL4863177)
Affinity DataKi:  349nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50028091BDBM50028091((1E)-5-methoxy-1-[4-(trifluoromethyl)phenyl]pentan...)
Affinity DataKi:  458nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578559BDBM50578559(CHEMBL4878226)
Affinity DataKi:  543nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578579BDBM50578579(CHEMBL4873377)
Affinity DataIC50: 881nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578568BDBM50578568(CHEMBL4865485)
Affinity DataKi:  1.46E+3nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578569BDBM50578569(CHEMBL4861511)
Affinity DataKi:  1.62E+3nMAssay Description:Displacement of [3H]citalopram from human SERT in HEK293 cells by Topcount scintillation analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578574BDBM50578574(CHEMBL4861851)
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Polish Academy of Sciences

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50578575BDBM50578575(CHEMBL4873453)
Affinity DataIC50: 5.66E+3nMAssay Description:Inhibition of human wild type SERT expressed in COS7 cells assessed as inhibition of [3H]5HT uptake measured for 40 hrs by scintillation counting ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed