Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50018397
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607981BDBM50607981(CHEMBL4782984)
Affinity DataKd:  900nMAssay Description:Binding affinity to human recombinant caspase 3 at 0.3125 to 5 uM measured after 400 secs by Surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607984BDBM50607984(CHEMBL4758598)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50071058BDBM50071058(CHEMBL301982 | cid_4274774 | (2R,4aS,6aS,12bR,14aS...)
Affinity DataEC50:  1.40E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607983BDBM50607983(CHEMBL1170915)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607985BDBM50607985(CHEMBL4763181)
Affinity DataEC50:  1.70E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607981BDBM50607981(CHEMBL4782984)
Affinity DataIC50: 1.70E+3nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607981BDBM50607981(CHEMBL4782984)
Affinity DataEC50:  1.80E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607982BDBM50607982(CHEMBL4789502)
Affinity DataEC50:  2.10E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607983BDBM50607983(CHEMBL1170915)
Affinity DataIC50: 2.40E+3nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607982BDBM50607982(CHEMBL4789502)
Affinity DataIC50: 2.90E+3nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608002BDBM50608002(CHEMBL5268260)
Affinity DataKd:  3.80E+3nMAssay Description:Binding affinity to human recombinant caspase 3 at 0.3125 to 5 uM measured after 400 secs by Surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607980BDBM50607980(CHEMBL4751648)
Affinity DataEC50:  4.40E+3nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607984BDBM50607984(CHEMBL4758598)
Affinity DataIC50: 6.20E+3nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607980BDBM50607980(CHEMBL4751648)
Affinity DataIC50: 6.70E+3nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607985BDBM50607985(CHEMBL4763181)
Affinity DataIC50: 1.00E+4nMAssay Description:Disruption of His-tagged full length HSP90 (unknown origin)/GST-tagged Cdc37 (unknown origin) measured after 1 hr by HTRF methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608003BDBM50608003(CHEMBL5287213)
Affinity DataEC50:  1.00E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607993BDBM50607993(CHEMBL5267627)
Affinity DataEC50:  1.41E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607996BDBM50607996(CHEMBL5289266)
Affinity DataEC50:  1.49E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607994BDBM50607994(CHEMBL5287882)
Affinity DataEC50:  1.57E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607988BDBM50607988(CHEMBL5291346)
Affinity DataEC50:  1.64E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608008BDBM50608008(CHEMBL5291409)
Affinity DataEC50:  1.75E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607995BDBM50607995(CHEMBL5278099)
Affinity DataEC50:  1.78E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608016BDBM50608016(CHEMBL5291370)
Affinity DataEC50:  1.82E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608000BDBM50608000(CHEMBL5290311)
Affinity DataEC50:  1.85E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607998BDBM50607998(CHEMBL5287993)
Affinity DataEC50:  1.87E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608012BDBM50608012(CHEMBL5286412)
Affinity DataEC50:  1.93E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607986BDBM50607986(CHEMBL5291361)
Affinity DataEC50:  1.93E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608015BDBM50608015(CHEMBL5272129)
Affinity DataEC50:  1.96E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607991BDBM50607991(CHEMBL5283469)
Affinity DataEC50:  1.97E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607999BDBM50607999(CHEMBL5284535)
Affinity DataEC50:  1.99E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607992BDBM50607992(CHEMBL5281460)
Affinity DataEC50:  2.01E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608013BDBM50608013(CHEMBL5287104)
Affinity DataEC50:  2.01E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608010BDBM50608010(CHEMBL5272214)
Affinity DataEC50:  2.03E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608014BDBM50608014(CHEMBL5269146)
Affinity DataEC50:  2.03E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607997BDBM50607997(CHEMBL5283733)
Affinity DataEC50:  2.04E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608007BDBM50608007(CHEMBL5284075)
Affinity DataEC50:  2.05E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608009BDBM50608009(CHEMBL5275224)
Affinity DataEC50:  2.05E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607987BDBM50607987(CHEMBL5267681)
Affinity DataEC50:  2.09E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607989BDBM50607989(CHEMBL5289163)
Affinity DataEC50:  2.12E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607990BDBM50607990(CHEMBL5287369)
Affinity DataEC50:  2.21E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608011BDBM50608011(CHEMBL5287464)
Affinity DataEC50:  2.23E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608006BDBM50608006(CHEMBL5267633)
Affinity DataEC50:  2.31E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608001BDBM50608001(CHEMBL5288481)
Affinity DataEC50:  2.39E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608004BDBM50608004(CHEMBL5265939)
Affinity DataEC50:  2.41E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608005BDBM50608005(CHEMBL5267595)
Affinity DataEC50:  2.43E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetCaspase-3(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608002BDBM50608002(CHEMBL5268260)
Affinity DataEC50:  2.55E+4nMAssay Description:Activation of caspase 3 in human MDA-MB-231 cells measured after 48 hrs by Plate reader methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed