Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50018256
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408828BDBM50408828(CHEMBL5270588)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of STAT3 (unknown origin) DNA binding activity by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353432BDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataKd:  504nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 700nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human Kasumi 1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human HL-60 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408825BDBM50408825(CHEMBL5280147)
Affinity DataIC50: 800nMAssay Description:Inhibition of STAT3 phosphorylation in human MOLM-13 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408830BDBM50408830(CHEMBL5284089)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to STAT3 (unknown origin) by MST analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408829BDBM50408829(CHEMBL5278293)
Affinity DataIC50: 3.57E+3nMAssay Description:Inhibition of STAT3 dependent transcriptional activity in human HeLa cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446146BDBM50446146(CHEMBL3108909)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of STAT3 (unknown origin) DNA binding activity by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50605550BDBM50605550(C-188-9 | Stat3 inhibitor c188-9 | Stat3 inhibitor...)
Affinity DataIC50: 4.00E+3nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408830BDBM50408830(CHEMBL5284089)
Affinity DataKd:  4.10E+3nMAssay Description:Binding affinity to recombinant human STAT3 by biolayer interferometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50446145BDBM50446145(CHEMBL3108910)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of STAT3 (unknown origin) DNA binding activity by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408831BDBM50408831(CHEMBL5271534)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to recombinant human STAT3 by biolayer interferometry analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50353432BDBM50353432(CHEMBL1829876 | US10196373, Compound 45O)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of STAT3 (unknown origin) DNA binding activity by EMSAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408835BDBM50408835(CHEMBL5267904)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of STAT3 (unknown origin) transcriptional activity expressed in MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408832BDBM50408832(CHEMBL4168135)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of STAT3 (unknown origin) dimerizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408827BDBM50408827(CHEMBL5282950)
Affinity DataKd:  1.55E+4nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408826BDBM50408826(CHEMBL5268863)
Affinity DataKd:  4.50E+4nMAssay Description:Binding affinity to STAT3 (unknown origin) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 5A(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408834BDBM50408834(CHEMBL5271424)
Affinity DataIC50: 5.08E+4nMAssay Description:Inhibition of STAT5a (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408834BDBM50408834(CHEMBL5271424)
Affinity DataIC50: 1.13E+5nMAssay Description:Inhibition of STAT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSignal transducer and activator of transcription 3(Human)
Cancer Hospital of The University of Chinese Academy of Sciences (Zhejiang Cancer Hospital)

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50408833BDBM50408833(CHEMBL5277569)
Affinity DataIC50: 1.60E+5nMAssay Description:Inhibition of STAT3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed