Compile Data Set for Download or QSAR
Report error Found 46 Enz. Inhib. hit(s) with all data for entry = 50018398
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001019BDBM50001019(CHEMBL316632 | 6,11-Dimethyl-3-phenethyl-1,2,3,4,5...)
Affinity DataKi:  0.200nMAssay Description:Binding affinity to mu opioid receptor (unknown origin) assessed as inhibition constant in presence of LevorphanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001043BDBM50001043(CHEMBL94350 | 6,11-Dimethyl-3-phenethyl-1,2,3,4,5,...)
Affinity DataKi:  3.90nMAssay Description:Displacement of [3H]pentazocine from guinea pig brain membrane sigma 1 receptor incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064196BDBM50064196((2S,6R,11S)-6,11-Dimethyl-3-[2-(methyl-phenyl-amin...)
Affinity DataKi:  5.60nMAssay Description:Displacement of [3H]pentazocine from guinea pig brain membrane sigma 1 receptor incubated for 150 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064195BDBM50064195((2S,6R,11S)-6,11-Dimethyl-3-(2-phenylamino-ethyl)-...)
Affinity DataKi:  5.90nMAssay Description:Displacement of [3H]pentazocine from guinea pig brain membrane sigma 1 receptor incubated for 150 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064196BDBM50064196((2S,6R,11S)-6,11-Dimethyl-3-[2-(methyl-phenyl-amin...)
Affinity DataKi:  29nMAssay Description:Displacement of [ 3H]-naloxone from rat brain membrane mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001043BDBM50001043(CHEMBL94350 | 6,11-Dimethyl-3-phenethyl-1,2,3,4,5,...)
Affinity DataKi:  55nMAssay Description:Binding affinity to mu opioid receptor (unknown origin) assessed as inhibition constant in presence of LevorphanolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50001019BDBM50001019(CHEMBL316632 | 6,11-Dimethyl-3-phenethyl-1,2,3,4,5...)
Affinity DataKi:  62nMAssay Description:Displacement of [3H]pentazocine from guinea pig brain membrane sigma 1 receptor incubated for 120 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Rat)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50064195BDBM50064195((2S,6R,11S)-6,11-Dimethyl-3-(2-phenylamino-ethyl)-...)
Affinity DataKi:  80nMAssay Description:Displacement of [ 3H]-naloxone from rat brain membrane mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580843BDBM50580843(CHEMBL5086571)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580830BDBM50580830(CHEMBL5070613)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608018BDBM50608018(CHEMBL5275633)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608017BDBM50608017(CHEMBL5287561)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608033BDBM50608033(CHEMBL5273639)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608032BDBM50608032(CHEMBL5286127)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608017BDBM50608017(CHEMBL5287561)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580843BDBM50580843(CHEMBL5086571)
Affinity DataKi:  100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608019BDBM50608019(CHEMBL5273191)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608018BDBM50608018(CHEMBL5275633)
Affinity DataKi:  100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608021BDBM50608021(CHEMBL5270180)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608020BDBM50608020(CHEMBL5271829)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608023BDBM50608023(CHEMBL5268264)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608022BDBM50608022(CHEMBL5283278)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608025BDBM50608025(CHEMBL5273601)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608024BDBM50608024(CHEMBL5271326)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608027BDBM50608027(CHEMBL5280075)
Affinity DataKi:  100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608026BDBM50608026(CHEMBL5284021)
Affinity DataKi:  100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608029BDBM50608029(CHEMBL5285872)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608028BDBM50608028(CHEMBL5281430)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608031BDBM50608031(CHEMBL5277867)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608030BDBM50608030(CHEMBL5285937)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608020BDBM50608020(CHEMBL5271829)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608019BDBM50608019(CHEMBL5273191)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608022BDBM50608022(CHEMBL5283278)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608021BDBM50608021(CHEMBL5270180)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608024BDBM50608024(CHEMBL5271326)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608023BDBM50608023(CHEMBL5268264)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608026BDBM50608026(CHEMBL5284021)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608025BDBM50608025(CHEMBL5273601)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608028BDBM50608028(CHEMBL5281430)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608027BDBM50608027(CHEMBL5280075)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608030BDBM50608030(CHEMBL5285937)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608029BDBM50608029(CHEMBL5285872)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608032BDBM50608032(CHEMBL5286127)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608031BDBM50608031(CHEMBL5277867)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50580830BDBM50580830(CHEMBL5070613)
Affinity DataKi: <100nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in HEK293 cells membrane incubated for 120 mins by MicroBeta scintillation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50608033BDBM50608033(CHEMBL5273639)
Affinity DataKi: <100nMAssay Description:Displacement of [3H]-DAMGO from human mu opioid receptor expressed in CHO-K1 cells membrane incubated for 60 mins by MicroBeta scintillation counter ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed