Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50014488
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576809BDBM50576809(CHEMBL4879321)
Affinity DataIC50: 52nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576809BDBM50576809(CHEMBL4879321)
Affinity DataIC50: 65nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576810BDBM50576810(CHEMBL4865182)
Affinity DataIC50: 72nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576810BDBM50576810(CHEMBL4865182)
Affinity DataIC50: 78nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576800BDBM50576800(CHEMBL4850746)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576800BDBM50576800(CHEMBL4850746)
Affinity DataIC50: 93nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50570254BDBM50570254(CHEMBL4865865)
Affinity DataIC50: 98nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576801BDBM50576801(CHEMBL4857716)
Affinity DataIC50: 100nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576801BDBM50576801(CHEMBL4857716)
Affinity DataIC50: 102nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576807BDBM50576807(CHEMBL4876793)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576799BDBM50576799(CHEMBL4854295)
Affinity DataIC50: 112nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50425732BDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataIC50: 117nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576802BDBM50576802(CHEMBL4865876)
Affinity DataIC50: 123nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576802BDBM50576802(CHEMBL4865876)
Affinity DataIC50: 126nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576805BDBM50576805(CHEMBL4852266)
Affinity DataIC50: 132nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576799BDBM50576799(CHEMBL4854295)
Affinity DataIC50: 145nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576805BDBM50576805(CHEMBL4852266)
Affinity DataIC50: 148nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576808BDBM50576808(CHEMBL4860814)
Affinity DataIC50: 151nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576808BDBM50576808(CHEMBL4860814)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576804BDBM50576804(CHEMBL4865067)
Affinity DataIC50: 170nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576806BDBM50576806(CHEMBL4871131)
Affinity DataIC50: 174nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576807BDBM50576807(CHEMBL4876793)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576798BDBM50576798(CHEMBL4851052)
Affinity DataIC50: 178nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576803BDBM50576803(CHEMBL4871015)
Affinity DataIC50: 191nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50570254BDBM50570254(CHEMBL4865865)
Affinity DataIC50: 191nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576806BDBM50576806(CHEMBL4871131)
Affinity DataIC50: 209nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576798BDBM50576798(CHEMBL4851052)
Affinity DataIC50: 219nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576804BDBM50576804(CHEMBL4865067)
Affinity DataIC50: 229nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576803BDBM50576803(CHEMBL4871015)
Affinity DataIC50: 257nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576796BDBM50576796(CHEMBL4868140)
Affinity DataIC50: 339nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576796BDBM50576796(CHEMBL4868140)
Affinity DataIC50: 398nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576794BDBM50576794(CHEMBL4866153)
Affinity DataIC50: 525nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576794BDBM50576794(CHEMBL4866153)
Affinity DataIC50: 646nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576793BDBM50576793(CHEMBL4861204)
Affinity DataIC50: 676nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576795BDBM50576795(CHEMBL4872153)
Affinity DataIC50: 759nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576795BDBM50576795(CHEMBL4872153)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576793BDBM50576793(CHEMBL4861204)
Affinity DataIC50: 1.38E+3nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576797BDBM50576797(CHEMBL4856041)
Affinity DataIC50: 1.66E+3nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576792BDBM50576792(CHEMBL4877559)
Affinity DataIC50: 5.01E+3nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576792BDBM50576792(CHEMBL4877559)
Affinity DataIC50: 1.12E+4nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576791BDBM50576791(CHEMBL4876455)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at AR F877L mutant (unknown origin) transfected in human LNCAP cells assessed as inhibition of R1881-stimulated receptor transcri...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576791BDBM50576791(CHEMBL4876455)
Affinity DataIC50: 1.50E+4nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Janssen Research and Development

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50576797BDBM50576797(CHEMBL4856041)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at wild type androgen receptor in castration-resistant human LNCaP cells assessed as inhibition of R1881-stimulated receptor tran...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed