Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50014698
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579208BDBM50579208(CHEMBL4867107)
Affinity DataIC50: 2nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579222BDBM50579222(CHEMBL4861383)
Affinity DataIC50: 2.30nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 518531BDBM518531(US11124518, Example 6 | 2-Allyl-1-(6-(2-hydroxypro...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 518527BDBM518527(US11124518, Example 2 | 2-Alyl-6-((2′,3̸...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 518526BDBM518526(US11124518, Example 1 | 2-Allyl-1-(6-(2-hydroxypro...)
Affinity DataIC50: 2.40nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 518538BDBM518538(US11124518, Example 13 | 2-Allyl-6-((2-(2-hydroxye...)
Affinity DataIC50: 2.5nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579228BDBM50579228(CHEMBL4867211)
Affinity DataIC50: 2.5nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 518540BDBM518540(US11124518, Example 16 | 2-Allyl-1-(6-(2-hydroxypr...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579225BDBM50579225(CHEMBL4874546)
Affinity DataIC50: 2.60nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579214BDBM50579214(CHEMBL4856035)
Affinity DataIC50: 2.60nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 518530BDBM518530(US11124518, Example 5 | 2-Allyl-1-(6-(2-hydroxypro...)
Affinity DataIC50: 2.60nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579218BDBM50579218(CHEMBL4876612)
Affinity DataIC50: 2.90nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579223BDBM50579223(CHEMBL4853285)
Affinity DataIC50: 3.10nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579221BDBM50579221(CHEMBL4866800)
Affinity DataIC50: 3.20nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579224BDBM50579224(CHEMBL4861351)
Affinity DataIC50: 3.20nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579227BDBM50579227(CHEMBL4847705)
Affinity DataIC50: 3.20nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579216BDBM50579216(CHEMBL4865963)
Affinity DataIC50: 3.30nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579213BDBM50579213(CHEMBL4853973)
Affinity DataIC50: 3.60nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579220BDBM50579220(CHEMBL4868683)
Affinity DataIC50: 3.70nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579219BDBM50579219(CHEMBL4857841)
Affinity DataIC50: 3.70nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240826BDBM50240826(AZD-1775 | MK-1775 | US11124518, Example AZD1775 |...)
Affinity DataIC50: 3.90nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 3.90nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579215BDBM50579215(CHEMBL4861168)
Affinity DataIC50: 4.60nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579211BDBM50579211(CHEMBL4871803)
Affinity DataIC50: 4.80nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579212BDBM50579212(CHEMBL4879157)
Affinity DataIC50: 5.20nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579210BDBM50579210(CHEMBL4853185)
Affinity DataIC50: 5.70nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579210BDBM50579210(CHEMBL4853185)
Affinity DataIC50: 5.70nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579209BDBM50579209(CHEMBL4874090)
Affinity DataIC50: 6.40nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579226BDBM50579226(CHEMBL4856253)
Affinity DataIC50: 12nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579229BDBM50579229(CHEMBL4863657)
Affinity DataIC50: 22nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK2(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 40nMAssay Description:Inhibition of PLK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 19(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 59nMAssay Description:Inhibition of YSK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 60nMAssay Description:Inhibition of EGFR d747-749/A750P mutant (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579231BDBM50579231(CHEMBL4847051)
Affinity DataIC50: 64nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK3(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 70nMAssay Description:Inhibition of PLK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetWee1-like protein kinase(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579230BDBM50579230(CHEMBL4877772)
Affinity DataIC50: 100nMAssay Description:Displacement of Alexa Fluor labelled kinase tracer178 from WEE1 (unknown origin) incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase PLK1(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 227nMAssay Description:Inhibition of PLK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579208BDBM50579208(CHEMBL4867107)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50240826BDBM50240826(AZD-1775 | MK-1775 | US11124518, Example AZD1775 |...)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Zentalis Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50579217BDBM50579217(CHEMBL4871593)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERGMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed