Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50003388
Affinity DataIC50: 230nMAssay Description:Inhibition of full-length human wild-type NNMT assessed as formation of MNA at 0.5 uM using nicotinamide as substrate and SAM as cofactor preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of full-length human wild-type NNMT assessed as formation of MNA at 0.5 uM using nicotinamide as substrate and SAM as cofactor preincubate...More data for this Ligand-Target Pair
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of endogenous human NNMT overexpressed in human U2OS cells assessed incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human NNMT preincubated for 30 mins followed by substrate, cofactor addition and measured after 60 mins using nicotinamide as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:Binding affinity to recombinant human NNMT SAM binding site expressed in Escherichia coli BL21 (DE3) using nicotinamide as substrate and AdoMet as co...More data for this Ligand-Target Pair
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of NNMT (unknown origin) assessed as formation of MNA using nicotinamide as substrate and SAM as cofactor by fluorescence based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of mouse NNMT preincubated for 30 mins followed by substrate, cofactor addition and measured after 60 mins using nicotinamide as substrate...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of endogenous mouse NNMT overexpressed in murine 3T3-L1 cells assessed incubated for 24 hrs by LC-MS/MS analysisMore data for this Ligand-Target Pair
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant human NNMT (1 to 270 residues) expressed in Escherichia coli BL21 (DE3) and measured upto 60 mins by fluorescence polarizat...More data for this Ligand-Target Pair
3D Structure (crystal)
Affinity DataIC50: 2.63E+4nMAssay Description:Binding affinity to recombinant human NNMT SAM binding site expressed in Escherichia coli BL21 (DE3) using nicotinamide as substrate and AdoMet as co...More data for this Ligand-Target Pair
Affinity DataIC50: 2.92E+4nMAssay Description:Inhibition of recombinant human NNMT assessed as formation of MNA using nicotinamide and AdoMet as substrate preincubated for 10 mins followed by sub...More data for this Ligand-Target Pair
