Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50015513
TargetCytochrome P450 2D6(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50121975BDBM50121975((6-Methoxy-quinolin-4-yl)-(5-vinyl-1-aza-bicyclo[2...)
Affinity DataIC50: 18nMAssay Description:Inhibition of CYP2D6 (unknown origin) using quinidine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCytochrome P450 3A4(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 8610BDBM8610(24F2-1,25(OH)D3 | Ketoconazole (k) | KTZ | 1-[4-(4...)
Affinity DataIC50: 46nMAssay Description:Inhibition of CYP3A4 (unknown origin) using ketoconazole as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50017376BDBM50017376(1-(4-tert-butylphenyl)-4-(4-(hydroxydiphenylmethyl...)
Affinity DataKi:  78nMAssay Description:Binding affinity to human ERG assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587164BDBM50587164(CHEMBL5089882)
Affinity DataIC50: 180nMAssay Description:Inhibition of CYP3A4 (unknown origin) using ketoconazole as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315702BDBM50315702(CHEMBL4166126)
Affinity DataIC50: 270nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50315702BDBM50315702(CHEMBL4166126)
Affinity DataIC50: 460nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587165BDBM50587165(CHEMBL5081981)
Affinity DataIC50: 900nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587166BDBM50587166(CHEMBL5090796)
Affinity DataIC50: 900nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587165BDBM50587165(CHEMBL5081981)
Affinity DataIC50: 900nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587164BDBM50587164(CHEMBL5089882)
Affinity DataIC50: 950nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587167BDBM50587167(CHEMBL5082833)
Affinity DataIC50: 950nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587166BDBM50587166(CHEMBL5090796)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587168BDBM50587168(CHEMBL5074613)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587164BDBM50587164(CHEMBL5089882)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587170BDBM50587170(CHEMBL5079136)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587164BDBM50587164(CHEMBL5089882)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of CYP2D6 (unknown origin) using quinidine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 84804BDBM84804(CHEMBL536514 | 1-azolyl-4-phenyl-2-butanone, 6a)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044424BDBM50044424(4-{2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazol-1-ylme...)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587169BDBM50587169(CHEMBL5075602)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587174BDBM50587174(CHEMBL5089974)
Affinity DataIC50: 8.34E+3nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587168BDBM50587168(CHEMBL5074613)
Affinity DataIC50: 1.12E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 84804BDBM84804(CHEMBL536514 | 1-azolyl-4-phenyl-2-butanone, 6a)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587179BDBM50587179(CHEMBL5084092)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535259BDBM50535259(CHEMBL4534531)
Affinity DataIC50: 1.44E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587170BDBM50587170(CHEMBL5079136)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50044424BDBM50044424(4-{2-[2-(4-Chloro-phenyl)-ethyl]-2-imidazol-1-ylme...)
Affinity DataIC50: 2.44E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587169BDBM50587169(CHEMBL5075602)
Affinity DataIC50: 2.47E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587180BDBM50587180(CHEMBL5083975)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50535259BDBM50535259(CHEMBL4534531)
Affinity DataIC50: 2.88E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587182BDBM50587182(CHEMBL5092763)
Affinity DataIC50: 3.10E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587183BDBM50587183(CHEMBL5072992)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587173BDBM50587173(CHEMBL5090858)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 2(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587167BDBM50587167(CHEMBL5082833)
Affinity DataIC50: 4.59E+4nMAssay Description:Inhibition of Sprague-Dawley rat brain microsome HO-2 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587177BDBM50587177(CHEMBL5071354)
Affinity DataIC50: 5.06E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587176BDBM50587176(CHEMBL563814)
Affinity DataIC50: 5.76E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587178BDBM50587178(CHEMBL5093716)
Affinity DataIC50: 6.48E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587175BDBM50587175(CHEMBL5091180)
Affinity DataIC50: 9.61E+4nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587171BDBM50587171(CHEMBL4571673)
Affinity DataIC50: 1.10E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587181BDBM50587181(CHEMBL5079290)
Affinity DataIC50: 2.24E+5nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed
TargetHeme oxygenase 1(Rat)
University of Catania

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50587172BDBM50587172(CHEMBL5078606)
Affinity DataIC50: 2.50E+6nMAssay Description:Inhibition of Sprague-Dawley rat spleen microsome HO-1 assessed as bilirubin formation incubated for 60 mins by double-beam spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/7/2023
Entry Details Article
PubMed