Compile Data Set for Download or QSAR
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Report error Found 34 Enz. Inhib. hit(s) with all data for entry = 50015097
TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582801(CHEMBL5076656)
Affinity DataKi:  0.0700nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  0.110nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582799(CHEMBL5094166)
Affinity DataKi:  0.120nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582800(CHEMBL5093567)
Affinity DataKi:  0.170nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50541586(CHEMBL4638245)
Affinity DataKi:  0.260nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582798(CHEMBL5082323)
Affinity DataKi:  0.870nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582795(CHEMBL5081455)
Affinity DataKi:  1.10nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582794(CHEMBL5077709)
Affinity DataKi:  1.30nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582793(CHEMBL5082956)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582791(CHEMBL5094070)
Affinity DataKi:  2.70nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582796(CHEMBL5085333)
Affinity DataKi:  7.10nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582790(CHEMBL5092888)
Affinity DataKi:  10nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582797(CHEMBL5084533)
Affinity DataKi:  11nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582792(CHEMBL5080026)
Affinity DataKi:  11nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetChymotrypsinogen B2(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  35nMAssay Description:Binding affinity to human chymotrypsin assessed as inhibition constant using 3-Carbomethoxypropionyl-L-arginyl-Lprolyl-L-tyrosine p-Nitroaniline as s...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasma kallikrein(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  44nMAssay Description:Binding affinity to human plasma kallikrein assessed as inhibition constant using H-D-Prolyl-L-phenylalanyl-L-arginine p-Nitroaniline as substrate me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582789(CHEMBL5094027)
Affinity DataKi:  171nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM241589(US9409908, 221 | US9951071, Example 221)
Affinity DataKi:  330nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetCoagulation factor XI(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50582788(CHEMBL5083482)
Affinity DataKi:  548nMAssay Description:Binding affinity to human coagulation factor 11a using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate assessed as inhibition constant...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetTrypsin(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  720nMAssay Description:Binding affinity to human trypsin assessed as inhibition constant using N-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-Larginine p-Nitroaniline and its gamm...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor VII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to recombinant human coagulation factor 7a assessed as inhibition constant using N-alpha-Benzyloxycarbonyl-D-arginyl-glycyl-Larginin...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProthrombin(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity to human thrombin assessed as inhibition constant using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate measured upto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetTissue-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to human tissue type plasminogen assessed as inhibition constant using Methanesulfonyl-D-Cyclohexylalanyl-glycylarginine p-Nitroanil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlasminogen(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  2.65E+3nMAssay Description:Binding affinity to human plasmin assessed as inhibition constant using H-D-Valyl-L-leucyl-L-lysine p-Nitroaniline as substrate measured upto 120 min...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor XII(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >3.00E+3nMAssay Description:Binding affinity to human coagulation factor 12a assessed as inhibition constant using H-D-Cyclohexylalanyl-glycyl-arginyl p-Nitroaniline as substrat...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetUrokinase-type plasminogen activator(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi:  3.90E+3nMAssay Description:Binding affinity to human urokinase assessed as inhibition constant using L-Pyroglutamyl-glycyl-L-arginine p-Nitroaniline as substrate upto 120 mins ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNeutrophil elastase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >8.00E+3nMAssay Description:Binding affinity to human neutrophil elastase assessed as inhibition constant using Methoxysuccinyl-L-alanyl-L-alanyl-L-prolylL-valine p-Nitroaniline...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetKallikrein-1(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >1.10E+4nMAssay Description:Binding affinity to human tissue kallikrein-1 assessed as inhibition constant using H-D-Valyl-L-leucyl-L-arginine 7-amino-4-trifluoromethylcoumarin a...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMyeloblastin(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >1.20E+4nMAssay Description:Binding affinity to human neutrophil proteinase 3 assessed as inhibition constant using Methoxysuccinyl-L-alanyl-L-alanyl-L-prolylL-valine p-Nitroani...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetChymase(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity to human mast cell chymase assessed as inhibition constant using Succinyl-L-alanyl-L-alanyl-L-prolyl-L phenylalanine p-Nitroaniline ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor X(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >1.30E+4nMAssay Description:Binding affinity to human coagulation factor 10a assessed as inhibition constant using N-Benzoyl-L-isoleucyl-L-glutamyl-glycyl-Larginine p-Nitroanili...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCathepsin G(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >2.00E+4nMAssay Description:Binding affinity to human neutrophil cathepsin G assessed as inhibition constant using Succinyl-L-alanyl-L-alanyl-L-prolyl-Lphenylalanine p-Nitroanil...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetVitamin K-dependent protein C(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >2.10E+4nMAssay Description:Binding affinity to human activated protein C assessed as inhibition constant using L-Pyroglutamyl-L-prolyl-L-arginine p-Nitroaniline as substrate me...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetCoagulation factor IX(Human)
Bristol Myers Squibb

Curated by ChEMBL
LigandPNGBDBM247411(US10336754, Example 353 | US11053247, Example 353 ...)
Affinity DataKi: >2.70E+4nMAssay Description:Binding affinity to human coagulation factor 9a assessed as inhibition constant using Methylsulfonyl-D-cyclohexylglycyl-glycylarginine 7-amino-4-meth...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed