Found 17 Enz. Inhib. hit(s) with all data for entry = 50014568 
Affinity DataIC50: 35nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 51nMAssay Description:Antagonist activity at mouse CaSRMore data for this Ligand-Target Pair
Affinity DataIC50: 110nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 250nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: 631nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Antagonist activity at human CaSR in human HEK293 cells measured after 5 mins by FLIPR assayMore data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >5.00E+4nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 5.00E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 8.00E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: >1.00E+4nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.30E+4nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 3.20E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 1.00E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
3D Structure (crystal)TargetNuclear receptor subfamily 1 group I member 2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataEC50: 2.50E+3nMAssay Description:Activation of full length human PXR expressed in human HepG2 cells co-expressing luciferase of CYP3A4 promoter transcription assessed as increase of ...More data for this Ligand-Target Pair
