Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50014728
Affinity DataIC50: 0.5nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 5.60nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of C-terminal GST-tagged full length human HDAC8 (518 to end residues) expressed in baculovirus expression system using Ac-peptide-AMC as ...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+3nMAssay Description:Inhibition of N-terminal FLAG-tagged full length human HDAC11 expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as substrate incubated...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC6 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human HDAC2 using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)(Human)
West China Hospital of Sichuan University
Curated by ChEMBL
West China Hospital of Sichuan University
Curated by ChEMBL
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of C-terminal His-tagged recombinant human HDAC3 (1 to 428 residues)/N-terminal GST-tagged recombinant human NCoR2 (395 to 489 residues) c...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged/C-terminal His-tagged human HDAC4 (627 to 1084 residues) expressed in baculovirus expression system using Ac-pept...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC5 (627 to 1084 residues) expressed in baculovirus expression system using Ac-peptide-AMC as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal GST-tagged full length human HDAC7 (518 to end residues) expressed in baculovirus expression system using Ac-peptide-AMC as ...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of C-terminal GST-tagged full length human HDAC9 (604 to 1066 residues) expressed in baculovirus expression system using Ac-peptide-AMC as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of N-terminal FLAG-tagged full length human HDAC10 (2 to 631 residues) expressed in baculovirus infected sf9 cells using Ac-peptide-AMC as...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of HDAC1 (unknown origin) using Ac-peptide-AMC as substrate incubated for 1 hr by fluorescence methodMore data for this Ligand-Target Pair
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of CYP1A2 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...More data for this Ligand-Target Pair
Affinity DataIC50: 6.92E+4nMAssay Description:Inhibition of CYP2E1 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...More data for this Ligand-Target Pair
Affinity DataIC50: 9.28E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C9 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2C19 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS an...More data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using probe substrate in presence of NADPH regenerating system incubated for 60 mins by UFLC-MS/MS ana...More data for this Ligand-Target Pair
