Compile Data Set for Download or QSAR
Report error Found 52 Enz. Inhib. hit(s) with all data for entry = 50015877
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590252BDBM50590252(CHEMBL5186900)
Affinity DataIC50: 280nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590252BDBM50590252(CHEMBL5186900)
Affinity DataIC50: 350nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590248BDBM50590248(CHEMBL5202822)
Affinity DataIC50: 460nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590248BDBM50590248(CHEMBL5202822)
Affinity DataIC50: 520nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590244BDBM50590244(CHEMBL5179649)
Affinity DataIC50: 1.00E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590240BDBM50590240(CHEMBL5188622)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590244BDBM50590244(CHEMBL5179649)
Affinity DataIC50: 1.10E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590240BDBM50590240(CHEMBL5188622)
Affinity DataIC50: 1.40E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590249BDBM50590249(CHEMBL5204073)
Affinity DataIC50: 2.30E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590236BDBM50590236(CHEMBL5193268)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590246BDBM50590246(CHEMBL5188850)
Affinity DataIC50: 2.40E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590232BDBM50590232(CHEMBL5171851)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590236BDBM50590236(CHEMBL5193268)
Affinity DataIC50: 2.50E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590250BDBM50590250(CHEMBL5179379)
Affinity DataIC50: 2.60E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590250BDBM50590250(CHEMBL5179379)
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590246BDBM50590246(CHEMBL5188850)
Affinity DataIC50: 2.80E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590243BDBM50590243(CHEMBL5202240)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590249BDBM50590249(CHEMBL5204073)
Affinity DataIC50: 3.10E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590239BDBM50590239(CHEMBL5206205)
Affinity DataIC50: 3.20E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259770BDBM50259770(CHEMBL4095869)
Affinity DataIC50: 3.30E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590237BDBM50590237(CHEMBL5188410)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590230BDBM50590230(CHEMBL5207441)
Affinity DataIC50: 3.40E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259770BDBM50259770(CHEMBL4095869)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590251BDBM50590251(CHEMBL5186879)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590247BDBM50590247(CHEMBL5179162)
Affinity DataIC50: 3.60E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590243BDBM50590243(CHEMBL5202240)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590233BDBM50590233(CHEMBL5170704)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590251BDBM50590251(CHEMBL5186879)
Affinity DataIC50: 3.70E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590247BDBM50590247(CHEMBL5179162)
Affinity DataIC50: 3.80E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590238BDBM50590238(CHEMBL5190591)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590239BDBM50590239(CHEMBL5206205)
Affinity DataIC50: 3.90E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590245BDBM50590245(CHEMBL5185625)
Affinity DataIC50: 4.00E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259769BDBM50259769(CHEMBL4068546)
Affinity DataIC50: 4.20E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259768BDBM50259768(CHEMBL4063297)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590230BDBM50590230(CHEMBL5207441)
Affinity DataIC50: 4.30E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590234BDBM50590234(CHEMBL5209033)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590232BDBM50590232(CHEMBL5171851)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590235BDBM50590235(CHEMBL5196367)
Affinity DataIC50: 4.40E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259768BDBM50259768(CHEMBL4063297)
Affinity DataIC50: 4.80E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590231BDBM50590231(CHEMBL5207291)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590234BDBM50590234(CHEMBL5209033)
Affinity DataIC50: 5.00E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50259769BDBM50259769(CHEMBL4068546)
Affinity DataIC50: 5.50E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590235BDBM50590235(CHEMBL5196367)
Affinity DataIC50: 5.60E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590238BDBM50590238(CHEMBL5190591)
Affinity DataIC50: 5.80E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590242BDBM50590242(CHEMBL5188785)
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590237BDBM50590237(CHEMBL5188410)
Affinity DataIC50: 5.90E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590245BDBM50590245(CHEMBL5185625)
Affinity DataIC50: 6.20E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590231BDBM50590231(CHEMBL5207291)
Affinity DataIC50: 6.30E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 4(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590233BDBM50590233(CHEMBL5170704)
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonist activity at human TLR4 in HEK-Blue hTLR4 cells assessed as inhibition of LPS-induced receptor activation preincubated with LPS followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetToll-like receptor 2(Human)
Tsinghua University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50590242BDBM50590242(CHEMBL5188785)
Affinity DataIC50: 6.50E+3nMAssay Description:Antagonist activity at human TLR2 in HEK-Blue hTLR2 cells assessed as inhibition of Pam3CSK4-induced receptor activation preincubated with Pam3CSK4 f...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
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