Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50016858
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3758BDBM3758(N-(3-Bromophenyl)-6-methoxy-1H-pyrimido[4,5-b]indo...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597827BDBM50597827(CHEMBL5184038)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597830BDBM50597830(CHEMBL5183413)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597828BDBM50597828(CHEMBL5187154)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597822BDBM50597822(CHEMBL5175208)
Affinity DataIC50: 9nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597826BDBM50597826(CHEMBL5169624)
Affinity DataIC50: 10nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5323BDBM5323(1-[3-(4-methylpiperazin-1-yl)propyl]-3-[5-(thiophe...)
Affinity DataIC50: 16nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597829BDBM50597829(CHEMBL5171763)
Affinity DataIC50: 21nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597820BDBM50597820(CHEMBL423224)
Affinity DataIC50: 31nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597823BDBM50597823(CHEMBL5172665)
Affinity DataIC50: 31nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5322BDBM5322(1-[3-(piperidin-1-yl)propyl]-3-[5-(thiophen-3-yl)p...)
Affinity DataIC50: 38nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597824BDBM50597824(CHEMBL5202879)
Affinity DataIC50: 40nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5324BDBM5324(dimethyl(3-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-i...)
Affinity DataIC50: 64nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3744BDBM3744(N-(3-bromophenyl)-5H-pyrimido[5,4-b]indol-4-amine ...)
Affinity DataIC50: 72nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597825BDBM50597825(CHEMBL5199108)
Affinity DataIC50: 84nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5320BDBM5320(1-[2-(piperidin-1-yl)ethyl]-3-[5-(thiophen-3-yl)py...)
Affinity DataIC50: 111nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5319BDBM5319(dimethyl(2-{3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-i...)
Affinity DataIC50: 115nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 5318BDBM5318(3-[5-(thiophen-3-yl)pyridin-3-yl]-1H-indole | 3-(5...)
Affinity DataIC50: 126nMAssay Description:Inhibition of VEGFR2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3746BDBM3746(N-benzyl-5H-pyrimido[5,4-b]indol-4-amine | Pyrimid...)
Affinity DataIC50: 460nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4000BDBM4000(N-phenyl-3-[2-({3-[2-(phenylcarbamoyl)ethyl]-1H-in...)
Affinity DataIC50: 850nMAssay Description:Inhibition of EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597831BDBM50597831(CHEMBL5182427)
Affinity DataIC50: 1.34E+3nMAssay Description:Inhibition of p60 c-src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3985BDBM3985(3-(2-{[3-(2-carboxyethyl)-7-methyl-1H-indol-2-yl]d...)
Affinity DataIC50: 1.50E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597821BDBM50597821(CHEMBL309276)
Affinity DataIC50: 1.62E+3nMAssay Description:Displacement of 32P-labeled ATP from EGFR derived from human A-431 cell membrane vesicles using copolymer of Glu/Ala/Tyr as substrate incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4033BDBM4033(6-methoxy-2-{[6-methoxy-1-methyl-3-(phenylcarbamoy...)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3749BDBM3749(N-cyclohexyl-5H-pyrimido[5,4-b]indol-4-amine | Pyr...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 3750BDBM3750(dimethyl(2-{5H-pyrimido[5,4-b]indol-4-ylamino}ethy...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of EGFR in human A-431 cell membrane vesicles using phospholipase C-gamma-1 as substrate incubated for 10 mins by scintillation counter me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597819BDBM50597819(CHEMBL5205062)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4032BDBM4032(2-{[1,6-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 4024BDBM4024(2-{[1,5-dimethyl-3-(phenylcarbamoyl)-1H-indol-2-yl...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of EGFR derived from human A-431 cells using copolymer of Glu/Ala/Tyr as substrate by scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Dr. Harisingh Gour University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50597832BDBM50597832(CHEMBL5184360)
Affinity DataIC50: 1.06E+5nMAssay Description:Inhibition of src (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed