Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50015144
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583291BDBM50583291(CHEMBL5085074)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583293BDBM50583293(CHEMBL5088008)
Affinity DataIC50: 200nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583295BDBM50583295(CHEMBL5093372)
Affinity DataIC50: 210nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583289BDBM50583289(CHEMBL5080803)
Affinity DataIC50: 230nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583290BDBM50583290(CHEMBL5088166)
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583294BDBM50583294(CHEMBL5072274)
Affinity DataIC50: 240nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583296BDBM50583296(CHEMBL5085633)
Affinity DataIC50: 250nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583302BDBM50583302(CHEMBL5071392)
Affinity DataIC50: 270nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583308BDBM50583308(CHEMBL5089203)
Affinity DataIC50: 270nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583288BDBM50583288(CHEMBL4794186 | US20240425441, Compound 45)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583307BDBM50583307(CHEMBL5072348)
Affinity DataIC50: 300nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583298BDBM50583298(CHEMBL4759754)
Affinity DataIC50: 340nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583292BDBM50583292(CHEMBL5073724)
Affinity DataIC50: 350nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583303BDBM50583303(CHEMBL5092055)
Affinity DataIC50: 410nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583304BDBM50583304(CHEMBL5077729)
Affinity DataIC50: 420nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583306BDBM50583306(CHEMBL5084797)
Affinity DataIC50: 560nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583301BDBM50583301(CHEMBL5078319)
Affinity DataIC50: 590nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583297BDBM50583297(CHEMBL5084822)
Affinity DataIC50: 710nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583299BDBM50583299(CHEMBL5084841)
Affinity DataIC50: 960nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583300BDBM50583300(CHEMBL5074759)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583305BDBM50583305(CHEMBL5079669)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Universite de Moncton

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50000541BDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of 5-LO in thapsigargin stimulated human PMNL cells assessed as reduction in 5-LO product level preincubated for 5 mins followed by thapsi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed