Compile Data Set for Download or QSAR
Report error Found 23 Enz. Inhib. hit(s) with all data for entry = 50016642
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592810BDBM50592810(CHEMBL5174113)
Affinity DataKi:  2.20nMAssay Description:Antagonist activity at human OX1R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592811BDBM50592811(CHEMBL5170308)
Affinity DataKi:  5.20nMAssay Description:Antagonist activity at human OX1R expressed in CHO-K1 cells assessed as inhibition of orexin-A-induced increase in calcium mobilization preincubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 386067BDBM386067(methyl (2R,3S)-3- ((methylsulfonyl)amino)-2-(((cis...)
Affinity DataEC50:  5.5nMAssay Description:Agonist activity at human OX2R expressed in CHO-K1 cells assessed as increase in calcium mobilization by Fluo-4-AM dye based fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596329BDBM50596329(CHEMBL5174799)
Affinity DataEC50:  9.20nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596326BDBM50596326(CHEMBL5176007)
Affinity DataEC50:  23nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596328BDBM50596328(CHEMBL5175432)
Affinity DataEC50:  24nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596330BDBM50596330(CHEMBL5171902)
Affinity DataEC50:  31nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596327BDBM50596327(CHEMBL5208933)
Affinity DataEC50:  51nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596329BDBM50596329(CHEMBL5174799)
Affinity DataEC50:  148nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596326BDBM50596326(CHEMBL5176007)
Affinity DataEC50:  232nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596330BDBM50596330(CHEMBL5171902)
Affinity DataEC50:  260nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596328BDBM50596328(CHEMBL5175432)
Affinity DataEC50:  473nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596327BDBM50596327(CHEMBL5208933)
Affinity DataEC50:  654nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596323BDBM50596323(CHEMBL5170597)
Affinity DataEC50:  873nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596324BDBM50596324(CHEMBL5179969)
Affinity DataEC50:  1.95E+3nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596321BDBM50596321(CHEMBL5202268)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596323BDBM50596323(CHEMBL5170597)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596322BDBM50596322(CHEMBL5171737)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596325BDBM50596325(CHEMBL5209514)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin/Hypocretin receptor type 1(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596324BDBM50596324(CHEMBL5179969)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX1R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596321BDBM50596321(CHEMBL5202268)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596322BDBM50596322(CHEMBL5171737)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetOrexin receptor type 2(Human)
University of Tsukuba

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596325BDBM50596325(CHEMBL5209514)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at OX2R (unknown origin) expressed in CHO cells by cell-based calcium assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed