Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50015150
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583310BDBM50583310(CHEMBL5082711)
Affinity DataIC50: 3.75E+3nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583310BDBM50583310(CHEMBL5082711)
Affinity DataIC50: 8.35E+3nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583311BDBM50583311(CHEMBL5084930)
Affinity DataIC50: 2.24E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583312BDBM50583312(CHEMBL5076143)
Affinity DataIC50: 2.25E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583312BDBM50583312(CHEMBL5076143)
Affinity DataIC50: 2.40E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583313BDBM50583313(CHEMBL5084225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583314BDBM50583314(CHEMBL5075910)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583310BDBM50583310(CHEMBL5082711)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes pre-incubated for 30 min in presence of NADPH by LC-LS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239382BDBM50239382(Lidamidine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583310BDBM50583310(CHEMBL5082711)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583311BDBM50583311(CHEMBL5084930)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583312BDBM50583312(CHEMBL5076143)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583313BDBM50583313(CHEMBL5084225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583314BDBM50583314(CHEMBL5075910)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of hERG expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239382BDBM50239382(Lidamidine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583311BDBM50583311(CHEMBL5084930)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583313BDBM50583313(CHEMBL5084225)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50583314BDBM50583314(CHEMBL5075910)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Cav1.2 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed
TargetSodium channel protein type 5 subunit alpha(Human)
University of North Carolina at Chapel Hill

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50239382BDBM50239382(Lidamidine)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human Nav1.5 expressed in HEK cells by patch clamp methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2023
Entry Details Article
PubMed