Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50016687
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as flurogenic substrate pre-incubated with compound for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as flurogenic substrate pre-incubated with compound for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as flurogenic substrate pre-incubated with compound for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataIC50: 7.50E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as flurogenic substrate pre-incubated with compound for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of SARS-CoV-2 3CL protease using MCA-AVLQSGFR-Lys(Dnp)-Lys-NH2 as flurogenic substrate pre-incubated with compound for 10 mins followed by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to SARS-CoV-2 3CL protease at 1.875 to 50 uM in presence of wallichins C by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataKd:  1.20E+4nMAssay Description:Binding affinity to SARS-CoV-2 3CL protease at 1.875 to 50 uM in presence of wallichins D by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataKd:  1.43E+4nMAssay Description:Binding affinity to SARS-CoV-2 3CL protease at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataKd:  1.66E+4nMAssay Description:Binding affinity to SARS-CoV-2 3CL protease at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetReplicase polyprotein 1ab(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataKd:  3.13E+4nMAssay Description:Binding affinity to SARS-CoV-2 3CL protease at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataKd:  6.47E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM in presence of wallichins D by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataKd:  6.47E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM in presence of wallichins C by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596581(CHEMBL5171650)
Affinity DataKd:  6.79E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetSpike glycoprotein(2019-nCoV)
Kunming Institute of Botany

Curated by ChEMBL
LigandPNGBDBM50596580(CHEMBL5173280)
Affinity DataKd:  9.17E+4nMAssay Description:Binding affinity to SARS-CoV-2 Spike glycoprotein receptor-binding domain at 1.875 to 50 uM by SPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed