Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50017640
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 200nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 400nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603575(CHEMBL5183018)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603572(CHEMBL5170243)
Affinity DataIC50: 8.70E+3nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603570(CHEMBL5190903)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603569(CHEMBL5182048)
Affinity DataIC50: 1.26E+4nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603573(CHEMBL5191304)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603574(CHEMBL5200803)
Affinity DataIC50: 3.55E+4nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603572(CHEMBL5170243)
Affinity DataIC50: 8.58E+4nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603571(CHEMBL5174327)
Affinity DataIC50: 1.54E+5nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603573(CHEMBL5191304)
Affinity DataIC50: 1.88E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603575(CHEMBL5183018)
Affinity DataIC50: 2.37E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603570(CHEMBL5190903)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603569(CHEMBL5182048)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603571(CHEMBL5174327)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603574(CHEMBL5200803)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603576(CHEMBL5198246)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of human COX-2 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by col...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50603576(CHEMBL5198246)
Affinity DataIC50: 3.80E+5nMAssay Description:Inhibition of full-length ovine COX-1 using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition and measured after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed