Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50016245
TargetIntegrase(Human immunodeficiency virus type 1)
Maharishi Markandeshwar (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)
Affinity DataEC50:  0.210nMAssay Description:Inhibition of HIV-1 integrase strand transfer activity incubated for 10 mins by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Maharishi Markandeshwar (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50183273((S)-6-(3-chloro-2-fluorobenzyl)-1-(1-hydroxy-3-met...)
Affinity DataEC50:  1nMAssay Description:Inhibition of HIV-1 integrase mutant strand transfer activity incubated for 10 mins by enzymatic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetCytochrome P450 3A4(Human)
Maharishi Markandeshwar (Deemed To Be University)

Curated by ChEMBL
LigandPNGBDBM50481218(DX-619 | CHEMBL390983)
Affinity DataKi:  6.79E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed