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Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50018536
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50609343(CHEMBL5269445)
Affinity DataIC50:  4.5nMAssay Description:Displacement of H3K27me3 from EED (unknown origin) by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50241662(CHEMBL4104741)
Affinity DataIC50:  18nMAssay Description:Inhibition of PRC2 complex of EZH2-EED-SUZ12 (unknown origin) using human nucleosome as substrate incubated for 70 mins in presence of [3H]SAMMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50236003(CHEMBL4096234)
Affinity DataIC50:  320nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50259910(CHEMBL4097892)
Affinity DataIC50:  890nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM223984(rac-(3R,4S)-1-(2-methoxybenzyl)-N,N-dimethyl-4-(1-...)
Affinity DataIC50:  1.57E+3nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50609344(CHEMBL5273243)
Affinity DataIC50:  8.76E+3nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50410562(CHEMBL5269781)
Affinity DataIC50:  1.16E+4nMAssay Description:Binding affinity to his tagged EED (1 to 441 residues) (unknown origin) incubated for 20 mins in presence of biotinylated H3K27me3 peptide (19 to 33 ...More data for this Ligand-Target Pair
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM225230(EED226 | US11013745, Compound EED226)
Affinity DataKd:  82nMAssay Description:Binding affinity to PRC2 complex of EZH2-EED-SUZ12 (unknown origin) assessed as dissociation constant by isothermal titration calorimetry methodMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50096619(1,8,9-Trihydroxy-3-methoxy-benzo[4,5]furo[3,2-c]ch...)
Affinity DataKd:  2.82E+3nMAssay Description:Binding affinity to EED (unknown origin) assessed as dissociation constant by SPR analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50609345(CHEMBL5289498)
Affinity DataKd:  0.320nMAssay Description:Binding affinity to C-terminal histidine tagged EED (unknown origin) expressed in Escherichia coli BL21(DE3) incubated for 15 mins by fluorescence po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetPolycomb protein EED(Human)
University of Jinany

Curated by ChEMBL
LigandPNGBDBM50241662(CHEMBL4104741)
Affinity DataKd:  1.5nMAssay Description:Binding affinity to EED (unknown origin) assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
In DepthDetails PubMed