Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50017702
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604214BDBM50604214(CHEMBL5170189)
Affinity DataIC50: 250nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604227BDBM50604227(CHEMBL5182403)
Affinity DataIC50: 290nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604201BDBM50604201(CHEMBL5203054)
Affinity DataIC50: 360nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604210BDBM50604210(CHEMBL5174303)
Affinity DataIC50: 360nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604212BDBM50604212(CHEMBL5190252)
Affinity DataIC50: 380nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604209BDBM50604209(CHEMBL5169392)
Affinity DataIC50: 390nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604204BDBM50604204(CHEMBL5188949)
Affinity DataIC50: 410nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604204BDBM50604204(CHEMBL5188949)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604193BDBM50604193(CHEMBL5187824)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604227BDBM50604227(CHEMBL5182403)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604208BDBM50604208(CHEMBL5202029)
Affinity DataIC50: 420nMAssay Description:Antagonist activity at 5-HT2B receptor (unknown origin) transfected in HEK293 cells assessed as beta-arrestin translocation by Tango assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604208BDBM50604208(CHEMBL5202029)
Affinity DataIC50: 440nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604200BDBM50604200(CHEMBL5205425)
Affinity DataIC50: 470nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604228BDBM50604228(CHEMBL5178349)
Affinity DataIC50: 520nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604226BDBM50604226(CHEMBL5172009)
Affinity DataIC50: 540nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604214BDBM50604214(CHEMBL5170189)
Affinity DataIC50: 570nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604225BDBM50604225(CHEMBL5201467)
Affinity DataIC50: 570nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604202BDBM50604202(CHEMBL5199983)
Affinity DataIC50: 610nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604218BDBM50604218(CHEMBL5197311)
Affinity DataIC50: 630nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604205BDBM50604205(CHEMBL5178255)
Affinity DataIC50: 670nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604206BDBM50604206(CHEMBL5197376)
Affinity DataIC50: 680nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604215BDBM50604215(CHEMBL5195432)
Affinity DataIC50: 700nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604227BDBM50604227(CHEMBL5182403)
Affinity DataIC50: 710nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604215BDBM50604215(CHEMBL5195432)
Affinity DataIC50: 770nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604199BDBM50604199(CHEMBL5178772)
Affinity DataIC50: 780nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604199BDBM50604199(CHEMBL5178772)
Affinity DataIC50: 790nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604211BDBM50604211(CHEMBL5186344)
Affinity DataIC50: 810nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604212BDBM50604212(CHEMBL5190252)
Affinity DataIC50: 880nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604204BDBM50604204(CHEMBL5188949)
Affinity DataKi:  900nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) assessed as displacement of radioligand at 10 uM by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604217BDBM50604217(CHEMBL5171368)
Affinity DataIC50: 900nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604219BDBM50604219(CHEMBL5176376)
Affinity DataIC50: 900nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604213BDBM50604213(CHEMBL2098167 | TCMDC-142373 | GSK1783663A)
Affinity DataIC50: 970nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604200BDBM50604200(CHEMBL5205425)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604222BDBM50604222(CHEMBL5187427)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604197BDBM50604197(CHEMBL5180340)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604213BDBM50604213(CHEMBL2098167 | TCMDC-142373 | GSK1783663A)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2B(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604193BDBM50604193(CHEMBL5187824)
Affinity DataKi:  1.30E+3nMAssay Description:Binding affinity to 5-HT2B receptor (unknown origin) assessed as displacement of radioligand at 10 uM by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604218BDBM50604218(CHEMBL5197311)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604206BDBM50604206(CHEMBL5197376)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604198BDBM50604198(CHEMBL5186455)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604193BDBM50604193(CHEMBL5187824)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604216BDBM50604216(CHEMBL5176001)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604198BDBM50604198(CHEMBL5186455)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604228BDBM50604228(CHEMBL5178349)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604193BDBM50604193(CHEMBL5187824)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604211BDBM50604211(CHEMBL5186344)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604202BDBM50604202(CHEMBL5199983)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604203BDBM50604203(CHEMBL5203795)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 1(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604222BDBM50604222(CHEMBL5187427)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC1 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
TargetAdenylate cyclase type 8(Human)
Purdue University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50604201BDBM50604201(CHEMBL5203054)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of Ca2+/ CAM stimulated human AC8 activity expressed in AC3 and AC6-knockout HEK293 cells assessed as A23187 stimulated cAMP accumulation ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/25/2023
Entry Details
PubMed
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