Compile Data Set for Download or QSAR
Report error Found 91 Enz. Inhib. hit(s) with all data for entry = 50016715
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596723BDBM50596723(CHEMBL5205903 | US20230348421, Compound 59)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]-Ketanserin from human 5-HT2A receptor at 50 nM incubated for 1 hr by microbeta scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596723BDBM50596723(CHEMBL5205903 | US20230348421, Compound 59)
Affinity DataIC50: 0.540nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596724BDBM50596724(CHEMBL5173703)
Affinity DataIC50: 1.90nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596729BDBM50596729(CHEMBL5189473 | US20230348421, Compound 82)
Affinity DataIC50: 2nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596723BDBM50596723(CHEMBL5205903 | US20230348421, Compound 59)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]- Mesulergine from human 5-HT2C receptor at 300 nM incubated for 1 hr by microbeta2 beta-counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596721BDBM50596721(CHEMBL5178732 | US20230348421, Compound 60)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596732BDBM50596732(CHEMBL5200074 | US20230348421, Compound 37)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596723BDBM50596723(CHEMBL5205903 | US20230348421, Compound 59)
Affinity DataIC50: 2.10nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596722BDBM50596722(CHEMBL5172822 | US20230348421, Compound 78)
Affinity DataIC50: 2.20nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596726BDBM50596726(CHEMBL5184906 | US20230348421, Compound 55)
Affinity DataIC50: 2.20nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596727BDBM50596727(CHEMBL5198741 | US20230348421, Compound 62)
Affinity DataIC50: 2.40nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596736BDBM50596736(CHEMBL5197899 | US20230348421, Compound 24)
Affinity DataIC50: 2.5nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596730BDBM50596730(CHEMBL5184297 | US20230348421, Compound 47)
Affinity DataIC50: 3.10nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596724BDBM50596724(CHEMBL5173703)
Affinity DataIC50: 3.10nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596736BDBM50596736(CHEMBL5197899 | US20230348421, Compound 24)
Affinity DataIC50: 3.5nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596729BDBM50596729(CHEMBL5189473 | US20230348421, Compound 82)
Affinity DataIC50: 3.80nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596728BDBM50596728(CHEMBL5175451 | US20230348421, Compound 94)
Affinity DataIC50: 4.30nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596737BDBM50596737(CHEMBL5191581 | US20230348421, Compound 41)
Affinity DataIC50: 4.30nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596725BDBM50596725(CHEMBL5198919 | US20230348421, Compound 92)
Affinity DataIC50: 4.60nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596726BDBM50596726(CHEMBL5184906 | US20230348421, Compound 55)
Affinity DataIC50: 4.70nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596722BDBM50596722(CHEMBL5172822 | US20230348421, Compound 78)
Affinity DataIC50: 6nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596725BDBM50596725(CHEMBL5198919 | US20230348421, Compound 92)
Affinity DataIC50: 6.5nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596741BDBM50596741(CHEMBL5185362 | US20230348421, Compound 26)
Affinity DataIC50: 6.90nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596728BDBM50596728(CHEMBL5175451 | US20230348421, Compound 94)
Affinity DataIC50: 7.60nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596735BDBM50596735(CHEMBL5208211)
Affinity DataIC50: 8.30nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596718BDBM50596718(CHEMBL5184703 | US20230348421, Compound 1)
Affinity DataIC50: 8.60nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596743BDBM50596743(CHEMBL5200788 | US20230348421, Compound 66)
Affinity DataIC50: 8.90nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596730BDBM50596730(CHEMBL5184297 | US20230348421, Compound 47)
Affinity DataIC50: 9.20nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596741BDBM50596741(CHEMBL5185362 | US20230348421, Compound 26)
Affinity DataIC50: 9.80nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596737BDBM50596737(CHEMBL5191581 | US20230348421, Compound 41)
Affinity DataIC50: 10nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596731BDBM50596731(CHEMBL5173149 | US20230348421, Compound 38)
Affinity DataIC50: 10nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596743BDBM50596743(CHEMBL5200788 | US20230348421, Compound 66)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596719BDBM50596719(CHEMBL5199061 | US20230348421, Compound 91)
Affinity DataIC50: 15nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596721BDBM50596721(CHEMBL5178732 | US20230348421, Compound 60)
Affinity DataIC50: 16nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596740BDBM50596740(CHEMBL5200155 | US20230348421, Compound 99)
Affinity DataIC50: 17nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596733BDBM50596733(CHEMBL5181432)
Affinity DataIC50: 18nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596739BDBM50596739(CHEMBL5194545 | US20230348421, Compound 98)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596738BDBM50596738(CHEMBL5205849 | US20230348421, Compound 50)
Affinity DataIC50: 21nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596718BDBM50596718(CHEMBL5184703 | US20230348421, Compound 1)
Affinity DataIC50: 23nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596735BDBM50596735(CHEMBL5208211)
Affinity DataIC50: 26nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139370BDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596744BDBM50596744(CHEMBL5192882)
Affinity DataIC50: 27nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596744BDBM50596744(CHEMBL5192882)
Affinity DataIC50: 30nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596727BDBM50596727(CHEMBL5198741 | US20230348421, Compound 62)
Affinity DataIC50: 33nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596731BDBM50596731(CHEMBL5173149 | US20230348421, Compound 38)
Affinity DataIC50: 33nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596740BDBM50596740(CHEMBL5200155 | US20230348421, Compound 99)
Affinity DataIC50: 33nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596720BDBM50596720(CHEMBL5200635)
Affinity DataIC50: 43nMAssay Description:Antagonist activity at 5-HT2A receptor (unknown origin) expressed in CHO-K1 cells assessed as reduction in intracellular Ca2+ mobilization incubated ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596732BDBM50596732(CHEMBL5200074 | US20230348421, Compound 37)
Affinity DataIC50: 43nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50596734BDBM50596734(CHEMBL5181200 | US20230348421, Compound 52)
Affinity DataIC50: 43nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Yantai University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 139370BDBM139370(ACP-103 | Pimavanserin | Pimavanserin hydrochlorid...)
Affinity DataIC50: 50nMAssay Description:Inverse agonist activity at 5-HT2A receptor (unknown origin) expressed in mouse NIH3T3 cells using o-nitrophenyl-D-galacto pyranoside incubated for 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
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