Compile Data Set for Download or QSAR
Report error Found 56 Enz. Inhib. hit(s) with all data for entry = 50018107
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404170(CHEMBL5288064)
Affinity DataIC50: 6nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50: 12nMAssay Description:Inhibition of equine serum BuchE using butyrylthiocholine iodide as substrate preincubated for 10 mins followed by substrate addition and measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50: 12nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404073(CHEMBL5281335)
Affinity DataIC50: 15nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404073(CHEMBL5281335)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate preincubated for 10 mins followed by enzyme addition and measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404157(CHEMBL5277689)
Affinity DataIC50: 17nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate preincubated for 10 mins followed by enzyme addition and measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404077(CHEMBL5284634)
Affinity DataIC50: 19nMAssay Description:Inhibition of MAO-B (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50562054(CHEMBL4781384)
Affinity DataKi:  20nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in human HEK293 cells incubated for 2 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404072(CHEMBL5266265)
Affinity DataIC50: 23nMAssay Description:Inhibition of MAO-A (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataKi:  27nMAssay Description:Displacement of [3H](+)-pentazocine from human sigma 1 receptor expressed in human HEK293 cells incubated for 2 hrs by liquid scintillation counting ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50468681(CHEMBL4287970)
Affinity DataIC50: 46nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404164(CHEMBL5272435)
Affinity DataIC50: 90nMAssay Description:Inhibition of recombinant human AchE using acetylthiocholine iodide as substrate and measured upto 2 mins by Ellman's methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404167(CHEMBL5289518)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MAO-B using tyramine as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404166(CHEMBL5267508)
Affinity DataIC50: 100nMAssay Description:Inhibition of human MAO-B using tyramine as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404165(CHEMBL5266377)
Affinity DataIC50: 100nMAssay Description:Inhibition of AchE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition and measured ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404162(CHEMBL5280309)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate preincubated for 10 mins followed by enzyme addition and measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404161(CHEMBL5269900)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate preincubated for 10 mins followed by enzyme addition and measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 272nMAssay Description:Inhibition of recombinant human MAO-B using p-tyramine as substrate preincubated for 15 mins in dark followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404158(CHEMBL5270089)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant human MAO-A using kynuramine as substrate preincubated for 10 mins followed by enzyme addition and measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 370nMAssay Description:Inhibition of electric eel AchE using acetylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured upto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404158(CHEMBL5270089)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human MAO-B using kynuramine as substrate preincubated for 10 mins followed by enzyme addition and measured after 20 mins b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404169(CHEMBL5284360)
Affinity DataIC50: 700nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404159(CHEMBL5289846)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of MAO-A (unknown origin) by fluorescence spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404170(CHEMBL5288064)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of equine serum BuChE using butyrylthiocholine chloride as substrate preincubated for 15 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human AchE expressed in human HEK293 cells using acetylthiocholine as substrate preincubated for 10 mins followed by substrate addition...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404159(CHEMBL5289846)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of MAO-B (unknown origin) by fluorescence spectrophotometer analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404169(CHEMBL5284360)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 15 mins followed by substrate addition by Ellman's metho...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404168(CHEMBL5287191)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 5 mins followed by substrate addition and measured upto ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404089(CHEMBL5267972)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human MAO-A using kynuramine as substrate preincubated for 5 mins followed by substrate addition and measured after 30 mins by spectros...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] A(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404166(CHEMBL5267508)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human MAO-A using tyramine as substrate preincubated for 10 mins followed by substrate addition and measured after 30 mins by fluoromet...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404155(CHEMBL5270046)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50553085(CHEMBL4762982)
Affinity DataIC50: 5.24E+3nMAssay Description:Inhibition of equine serum BuchE using S-butyrylthiocholine iodide as substrate preincubated for 6 mins followed by substrate addition and measured u...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 5.58E+3nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate measured after 3 mins by DTNB reagent based UV/Vis spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404160(CHEMBL5278858)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of BuChE (unknown origin) using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50562049(CHEMBL4776765)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of recombinant human MAO-B expressed in baculovirus-infected insect cells using p-tyramine as substrate preincubated for 30 mins followed ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404094(CHEMBL5265926)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of BuChE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 9.60E+3nMAssay Description:Inhibition of LOX15 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404155(CHEMBL5270046)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid as substrate preincubated for 5 mins followed by substrate addition by microplate spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404160(CHEMBL5278858)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of AChE (unknown origin) using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition by Ellman's m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404155(CHEMBL5270046)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human BuChE using butyrylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAmine oxidase [flavin-containing] B(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404163(CHEMBL5272826)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human MAO-B using tyramine as substrate preincubated for 30 mins followed by substrate addition and measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human AChE using acetylthiocholine as substrate preincubated for 15 mins followed by substrate addition and measured after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetProstaglandin G/H synthase 2(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404155(CHEMBL5270046)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of COX2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50562062(CHEMBL4754186)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404155(CHEMBL5270046)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of recombinant human BACE-1 expressed in baculovirus using Rh-EVNLDAEFK-Quencher as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404155(CHEMBL5270046)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of LOX15 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human LOX5 using arachidonic acid preincubated for 10 mins followed by substrate addition by microplate spectrophotometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404154(CHEMBL5270908)
Affinity DataIC50: 1.53E+4nMAssay Description:Inhibition of LOX5 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Jamia Millia Islamia

Curated by ChEMBL
LigandPNGBDBM50404156(CHEMBL5272243)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of BACE-1(unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
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