Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50018109
TargetInsulin-like growth factor 1 receptor(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50: 35nMAssay Description:Inhibition of full-length human IGF1R autophosphorylation expressed in mouse NIH3T3 cells using poly(Glu:Tyr) as substrate in presence of ATP preincu...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInsulin receptor(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50315887((1s,3s)-3-(8-amino-1-(2-phenylquinolin-7-yl)imidaz...)
Affinity DataIC50: 75nMAssay Description:Inhibition of recombinant human IR autophosphorylation using poly(Glu:Tyr) as substrate in presence of ATP by ELISA-based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 86nMAssay Description:Inhibition of GST-tagged recombinant human IGF1R ( 950 to 1337 residues) autophosphorylation expressed in mouse NWT-21 cells preincubated for 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetInsulin receptor(Human)
University of Leeds

Curated by ChEMBL
LigandPNGBDBM50157879(CHEMBL1614712)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of GST-tagged recombinant human IR ( 919 to 1343 residues) autophosphorylation expressed in mouse NIH-3T3-A14 cells preincubated for 90 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed