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Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50018114
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404376(CHEMBL5273773)
Affinity DataKi:  90nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase Mdm2(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50229787((4S,5R)-Nutlin-3 | (rac)-(4,5-bis(4-chlorophenyl)-...)
Affinity DataKi:  150nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
TargetTranscription intermediary factor 1-alpha(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50150812(CHEMBL3775853 | US10702504, Compound D)
Affinity DataIC50:  218nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase RNF114(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404380(CHEMBL5265809)
Affinity DataIC50:  240nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404379(CHEMBL5184599)
Affinity DataIC50:  247nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetTranscription intermediary factor 1-alpha(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404377(CHEMBL5276376)
Affinity DataIC50:  338nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404384(CHEMBL5269969)
Affinity DataIC50:  540nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase RNF4(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404382(CHEMBL5274757)
Affinity DataIC50:  540nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein fem-1 homolog B(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404383(CHEMBL5269604)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetE3 ubiquitin-protein ligase RNF4(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404381(CHEMBL5274740)
Affinity DataIC50:  1.80E+3nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein cereblon(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404378(CHEMBL5275511)
Affinity DataEC50:  79nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
Targetvon Hippel-Lindau disease tumor suppressor(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404375(CHEMBL5274307)
Affinity DataKd:  11nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein cereblon(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM50404379(CHEMBL5184599)
Affinity DataEC50:  703nMAssay Description:In vitro antagonism of the 5-HT-3 receptor determined by inhibition of 5-HT-induced depolarization of the isolated rat vagus nerve.More data for this Ligand-Target Pair
In DepthDetails PubMed