Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50016814
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597448(CHEMBL5180195)
Affinity DataIC50: 280nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597449(CHEMBL5170305)
Affinity DataIC50: 290nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597451(CHEMBL5202404)
Affinity DataIC50: 560nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597450(CHEMBL5208383)
Affinity DataIC50: 850nMAssay Description:Inhibition of human full length USP8 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597468(CHEMBL5184337)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597448(CHEMBL5180195)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597463(CHEMBL5176518)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597452(CHEMBL5171659)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) expressed in Escherichia coli BL21 (DE3) cells using ubiquitin-rhodamine -110 as substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597449(CHEMBL5170305)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of human full length USP7 overexpressed in baculovirus-infected insect cells using ubiquitin-C-terminal 7-amido-4-methylcoumarin as substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597469(CHEMBL5197403)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597468(CHEMBL5184337)
Affinity DataKd:  4.70E+3nMAssay Description:Binding affinity to N-terminal His6-tagged USP8 catalytic domain (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597467(CHEMBL5206972)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 7(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597452(CHEMBL5171659)
Affinity DataIC50: 1.05E+4nMAssay Description:Inhibition of USP7 (unknown origin) by surface plasmon resonance methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597465(CHEMBL5205340)
Affinity DataIC50: 1.55E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597455(CHEMBL5206674)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597457(CHEMBL4469440)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597464(CHEMBL5181521)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597462(CHEMBL4536844)
Affinity DataIC50: 1.65E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597456(CHEMBL5198716)
Affinity DataIC50: 1.76E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597458(CHEMBL4591454)
Affinity DataIC50: 1.83E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597466(CHEMBL5170419)
Affinity DataIC50: 2.35E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597454(CHEMBL5175647)
Affinity DataIC50: 2.45E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597453(CHEMBL4567355)
Affinity DataIC50: 3.16E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597459(CHEMBL5170083)
Affinity DataIC50: 3.60E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597453(CHEMBL4567355)
Affinity DataKd:  4.36E+4nMAssay Description:Binding affinity to N-terminal His6-tagged USP8 catalytic domain (734 to 1110 residues) (unknown origin) expressed in Escherichia coli BL21 (DE3) cel...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597461(CHEMBL5180339)
Affinity DataIC50: 4.37E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 8(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597460(CHEMBL5185694)
Affinity DataIC50: 4.52E+4nMAssay Description:Inhibition of N-terminal His6-tagged USP8 (unknown origin) catalytic domain (734 to 1110 residues) expressed in Escherichia coli BL21 (DE3) cells ass...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed
TargetUbiquitin carboxyl-terminal hydrolase 2(Human)
China Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50597468(CHEMBL5184337)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of USP2 (267 to 599 residues) (unknown origin) catalytic domain expressed in Escherichia coli BL21 (DE3) cells using ubiquitin-rhodamine -...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2023
Entry Details
PubMed