Compile Data Set for Download or QSAR
Report error Found 19 Enz. Inhib. hit(s) with all data for entry = 50016338
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594333(CHEMBL5174419)
Affinity DataIC50: 200nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM589235(US11555009, Compound 15 | US11555009, Compound 29)
Affinity DataIC50: 400nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM589236(US11555009, Compound 17)
Affinity DataIC50: 500nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594336(CHEMBL5176527)
Affinity DataIC50: 600nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594337(CHEMBL5176730)
Affinity DataIC50: 700nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594335(CHEMBL4436398)
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594341(CHEMBL5173835)
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594340(CHEMBL5171501)
Affinity DataIC50: 900nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594345(CHEMBL5190268)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594339(CHEMBL5190139)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM589231(US11555009, Compound 5)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594342(CHEMBL5175318)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594334(CHEMBL5206682)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594338(CHEMBL5204337)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594343(CHEMBL5190372)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM477000(US11555009, Compound 1)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594344(CHEMBL5186694)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50594332(CHEMBL5203848)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM477001(US11555009, Compound 2)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of N-terminal His-tagged human FTO expressed in Escherichia coli BL21(DE3) by PAGE based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2023
Entry Details
PubMed