Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50016142
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592766BDBM50592766(CHEMBL5175785)
Affinity DataIC50: 24nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592758BDBM50592758(CHEMBL5188138)
Affinity DataIC50: 31nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 49nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592767BDBM50592767(CHEMBL5177655)
Affinity DataIC50: 56nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592757BDBM50592757(CHEMBL5174143)
Affinity DataIC50: 61nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 6(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592757BDBM50592757(CHEMBL5174143)
Affinity DataIC50: 106nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 107nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 219nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592763BDBM50592763(CHEMBL5208908)
Affinity DataIC50: 220nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592758BDBM50592758(CHEMBL5188138)
Affinity DataIC50: 343nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592765BDBM50592765(CHEMBL5188938)
Affinity DataIC50: 368nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592759BDBM50592759(CHEMBL5183844)
Affinity DataIC50: 608nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592762BDBM50592762(CHEMBL5205762)
Affinity DataIC50: 632nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592764BDBM50592764(CHEMBL5200049)
Affinity DataIC50: 648nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 1(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592757BDBM50592757(CHEMBL5174143)
Affinity DataIC50: 655nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592760BDBM50592760(CHEMBL5183214)
Affinity DataIC50: 693nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592761BDBM50592761(CHEMBL5195862)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592758BDBM50592758(CHEMBL5188138)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of His-tagged N-terminal recombinant HSP90alpha (unknown origin) expressed in Escherichia coli BL21 (DE3) incubated for 4 hrs by fluoresce...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 3(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592757BDBM50592757(CHEMBL5174143)
Affinity DataIC50: 1.54E+3nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50592757BDBM50592757(CHEMBL5174143)
Affinity DataIC50: 1.69E+3nMAssay Description:Inhibition of HDAC7 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMed
TargetHistone deacetylase 7(Human)
Keimyung University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 19149BDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using fluorogenic substrate incubated for 30 mins by fluorescence plate readerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/20/2023
Entry Details
PubMedPDB3D3D Structure (crystal)