Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50015937
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590686(CHEMBL5208148)
Affinity DataIC50: 0.710nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590686(CHEMBL5208148)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590686(CHEMBL5208148)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590684(CHEMBL5204689)
Affinity DataIC50: 2.10nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590683(CHEMBL5176898)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590684(CHEMBL5204689)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590683(CHEMBL5176898)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of ALK (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590684(CHEMBL5204689)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590683(CHEMBL5176898)
Affinity DataIC50: 6.60nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 10nMAssay Description:Inhibition of ALK L1196M mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetALK tyrosine kinase receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 112nMAssay Description:Inhibition of ALK G1202R mutant (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590686(CHEMBL5208148)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590682(CHEMBL5192545)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50436850(CHEMBL2403108 | CERITINIB | US10053458, Comparativ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590683(CHEMBL5176898)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590685(CHEMBL5180262)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetEpidermal growth factor receptor(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50590684(CHEMBL5204689)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of EGFR (unknown origin) incubated for 1 hr and measured by mobility shift assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed