Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015953
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Modern University For Technology and Information Mti

Curated by ChEMBL
LigandPNGBDBM7960(CHEMBL305513 | JMC524454 Compound 5 | 1H-1,3-benzo...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO-JG21 LasR co-transfected with LVAgfp reporter assessed as inhibition of GFP production by fluorescence based...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Modern University For Technology and Information Mti

Curated by ChEMBL
LigandPNGBDBM7960(CHEMBL305513 | JMC524454 Compound 5 | 1H-1,3-benzo...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO-JP2 LasR co-transfected with LVAgfp reporter assessed as inhibition of GFP production by fluorescence based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHTH-type quorum-sensing regulator RhlR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Modern University For Technology and Information Mti

Curated by ChEMBL
LigandPNGBDBM14324(5,6-dimethyl-1H-1,3-benzodiazol-2-amine | Fragment...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 RhlR co-transfected with LVAgfp reporter assessed as inhibition of GFP production measured after 12 to 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Modern University For Technology and Information Mti

Curated by ChEMBL
LigandPNGBDBM14324(5,6-dimethyl-1H-1,3-benzodiazol-2-amine | Fragment...)
Affinity DataIC50: 3.75E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LasR co-transfected with LVAgfp reporter assessed as inhibition of GFP production measured after 12 to 24 h...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetHTH-type quorum-sensing regulator RhlR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Modern University For Technology and Information Mti

Curated by ChEMBL
LigandPNGBDBM7960(CHEMBL305513 | JMC524454 Compound 5 | 1H-1,3-benzo...)
Affinity DataIC50: 2.85E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 RhlRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetTranscriptional activator protein LasR(Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 /...)
Modern University For Technology and Information Mti

Curated by ChEMBL
LigandPNGBDBM7960(CHEMBL305513 | JMC524454 Compound 5 | 1H-1,3-benzo...)
Affinity DataIC50: 3.99E+5nMAssay Description:Inhibition of Pseudomonas aeruginosa PAO1 LasRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed