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Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50019910
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 40nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624581(CHEMBL5396142)
Affinity DataIC50: 1.23E+3nMAssay Description:Inhibition of recombinant human BACE1 using fluorogenic polypeptide Mca-SEVNLDAEFRK(Dpn)RRNH2 as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624581(CHEMBL5396142)
Affinity DataIC50: 1.31E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624584(CHEMBL5419495)
Affinity DataIC50: 1.72E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624575(CHEMBL5430322)
Affinity DataIC50: 1.81E+3nMAssay Description:Inhibition of recombinant human BACE1 using fluorogenic polypeptide Mca-SEVNLDAEFRK(Dpn)RRNH2 as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624583(CHEMBL5416204)
Affinity DataIC50: 2.14E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624582(CHEMBL5439636)
Affinity DataIC50: 2.24E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624581(CHEMBL5396142)
Affinity DataKi:  2.64E+3nMAssay Description:Competitive inhibition of electric eel AChE assessed as dissociation constant using acetylthiocholine as substrate by Lineweaver-Burk plot analysisMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624574(CHEMBL5397599)
Affinity DataIC50: 3.29E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624577(CHEMBL5425139)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 3.55E+3nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624579(CHEMBL5432645)
Affinity DataIC50: 4.07E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624580(CHEMBL5408041)
Affinity DataIC50: 4.55E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 6.30E+3nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624586(CHEMBL5438388)
Affinity DataIC50: 6.75E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624572(CHEMBL5433782)
Affinity DataIC50: 7.28E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624563(CHEMBL5401281)
Affinity DataIC50: 9.31E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624576(CHEMBL5413089)
Affinity DataIC50: 9.69E+3nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624574(CHEMBL5397599)
Affinity DataIC50: 9.98E+3nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624566(CHEMBL5406371)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624578(CHEMBL5397716)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624570(CHEMBL5405322)
Affinity DataIC50: 1.13E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624571(CHEMBL5421502)
Affinity DataIC50: 1.14E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624571(CHEMBL5421502)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624564(CHEMBL5429686)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624570(CHEMBL5405322)
Affinity DataIC50: 1.24E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624575(CHEMBL5430322)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624587(CHEMBL5409761)
Affinity DataIC50: 1.35E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624569(CHEMBL5407586)
Affinity DataIC50: 1.42E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50535290(CHEMBL4444849)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of GSK-3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624562(CHEMBL5414445)
Affinity DataIC50: 1.57E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624569(CHEMBL5407586)
Affinity DataIC50: 1.63E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624568(CHEMBL5434920)
Affinity DataIC50: 1.66E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624565(CHEMBL5440364)
Affinity DataIC50: 1.68E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624568(CHEMBL5434920)
Affinity DataIC50: 1.86E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624563(CHEMBL5401281)
Affinity DataIC50: 2.14E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624561(CHEMBL5395336)
Affinity DataIC50: 2.27E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624575(CHEMBL5430322)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624567(CHEMBL5413436)
Affinity DataIC50: 2.59E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of recombinant human BACE1 using fluorogenic polypeptide Mca-SEVNLDAEFRK(Dpn)RRNH2 as substrate incubated for 60 mins by FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetBeta-secretase 1(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50375219(CHEMBL258939)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of BACE1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624566(CHEMBL5406371)
Affinity DataIC50: 2.84E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624576(CHEMBL5413089)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624578(CHEMBL5397716)
Affinity DataIC50: 3.11E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624581(CHEMBL5396142)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624585(CHEMBL5404997)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624561(CHEMBL5395336)
Affinity DataIC50: 3.57E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Electric eel)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624573(CHEMBL5401344)
Affinity DataIC50: 3.65E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetCholinesterase(Horse)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50624577(CHEMBL5425139)
Affinity DataIC50: 4.42E+4nMAssay Description:Inhibition of equine serum BuChE using butylthiocholine iodine as substrate preincubated for 20 mins followed by substrate addition and measured afte...More data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
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