Compile Data Set for Download or QSAR
maximum 50k data
Found 11 Enz. Inhib. hit(s) with all data for entry = 50016172
TargetUDP-glucuronosyltransferase 1A1(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of UGT1A1(unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP1A2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP2B6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP2C8 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP2C9 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataIC50: >1.33E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataEC50: >5.00E+3nMAssay Description:Induction of CYP2B6 in human hepatocyteMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataEC50: >5.00E+3nMAssay Description:Induction of CYP3A4 in human hepatocyteMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Bristol Myers Squibb Research And Early Development

Curated by ChEMBL
LigandPNGBDBM372346(Method A: (R)-4-((1R,3aS,5aR,5bR,7aR,11aS,11bR,13a...)
Affinity DataEC50: >5.00E+3nMAssay Description:Induction of CYP1A2 in human hepatocyteMore data for this Ligand-Target Pair
In DepthDetails PubMed