Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50018133
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405407(CHEMBL5285361)
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405402(CHEMBL5267945)
Affinity DataIC50: 3nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405385(CHEMBL5285746)
Affinity DataIC50: 5nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM514529(N-(2-aminoethyl)-4-[[2-(5-chloro-2-fluoro-phenyl)-...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405403(CHEMBL5274165)
Affinity DataIC50: 7nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405404(CHEMBL5268400)
Affinity DataIC50: 12nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405409(CHEMBL5267264)
Affinity DataIC50: 14nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280348(N-(2-amino-2-oxo-ethyl)-4-[[2-(5-chloro-2-fluoro-p...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280340((S)-4-(2-(5-chloro-2-fluorophenyl)-5-isopropylpyri...)
Affinity DataIC50: 20nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405408(CHEMBL5290233)
Affinity DataIC50: 21nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280337((S)-4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280347(N-(2-acetamidoethyl)-4-[[2-(5-chloro-2-fluoro-phen...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405410(CHEMBL5266024)
Affinity DataIC50: 37nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280351(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405405(CHEMBL5287924)
Affinity DataIC50: 40nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405406(CHEMBL5285227)
Affinity DataIC50: 41nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetActivin receptor type-1B(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 57nMAssay Description:Inhibition of ALK4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405413(CHEMBL5273556)
Affinity DataIC50: 71nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405412(CHEMBL5276114)
Affinity DataIC50: 75nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405411(CHEMBL5277114)
Affinity DataIC50: 79nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405415(CHEMBL5278370)
Affinity DataIC50: 368nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405414(CHEMBL5276307)
Affinity DataIC50: 605nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetSerine/threonine-protein kinase receptor R3(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 7.29E+3nMAssay Description:Inhibition of ALK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetTGF-beta receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM50405416(CHEMBL5269560)
Affinity DataIC50: 7.45E+3nMAssay Description:Inhibition of human ALK5 autophosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1B(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ALK6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetBone morphogenetic protein receptor type-1A(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ALK3 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed
TargetActivin receptor type-1(Human)
Integral Biosciences

Curated by ChEMBL
LigandPNGBDBM280355(4-[[2-(5-chloro-2-fluoro-phenyl)-5-isopropyl-4-pyr...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of ALK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMed