Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50019938
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Institute of Organic Synthesis and Photoreactivity - National Research Council

Curated by ChEMBL
LigandPNGBDBM321290(N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...)
Affinity DataIC50: 370nMAssay Description:Inhibition of full length recombinant SMYD3 (unknown origin) measured at 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Institute of Organic Synthesis and Photoreactivity - National Research Council

Curated by ChEMBL
LigandPNGBDBM50624841(CHEMBL5431436)
Affinity DataIC50: 689nMAssay Description:Inhibition of full length recombinant SMYD3 (unknown origin) measured at 24 hrsMore data for this Ligand-Target Pair
Ligand InfoSimilars
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Institute of Organic Synthesis and Photoreactivity - National Research Council

Curated by ChEMBL
LigandPNGBDBM321290(N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...)
Affinity DataKi:  6.11E+3nMAssay Description:Binding affinity to full length recombinant SMYD3 (unknown origin) overexpressed in Escherichia coli Rosetta cells assessed as inhibition constant me...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Institute of Organic Synthesis and Photoreactivity - National Research Council

Curated by ChEMBL
LigandPNGBDBM321290(N-(1-(2-chloroacetyl)piperidin-4-yl)-5- cyclopropy...)
Affinity DataKd:  1.30E+4nMAssay Description:Binding affinity to full length recombinant SMYD3 (unknown origin) overexpressed in Escherichia coli Rosetta cells assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetHistone-lysine N-methyltransferase SMYD3(Human)
Institute of Organic Synthesis and Photoreactivity - National Research Council

Curated by ChEMBL
LigandPNGBDBM50624840(CHEMBL5413222)
Affinity DataKd:  3.20E+4nMAssay Description:Binding affinity to full length recombinant SMYD3 (unknown origin) overexpressed in Escherichia coli Rosetta cells assessed as dissociation constant ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2024
Entry Details
PubMed