Compile Data Set for Download or QSAR
Report error Found 51 Enz. Inhib. hit(s) with all data for entry = 50035686
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50367548BDBM50367548(CHEMBL1794921)
Affinity DataEC50:  50nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014324BDBM50014324(CHEMBL29669 | 5-[Bis-(4-chloro-phenyl)-methyl]-pyr...)
Affinity DataEC50:  55nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024481BDBM50024481((4-Chloro-phenyl)-pyrimidin-5-yl-(4-trifluoromethy...)
Affinity DataEC50:  66nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50014815BDBM50014815(CHEMBL29904 | Bis-(4-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  71nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024516BDBM50024516(5-[Bis-(4-chloro-phenyl)-fluoro-methyl]-pyrimidine...)
Affinity DataEC50:  78nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024524BDBM50024524(5-[1,1-Bis-(4-chloro-phenyl)-ethyl]-pyrimidine | C...)
Affinity DataEC50:  82nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024513BDBM50024513(6-Acetylsulfanyl-8-[2-[(4-amino-2-methyl-pyrimidin...)
Affinity DataEC50:  140nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024522BDBM50024522((4-Chloro-phenyl)-(4-fluoro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  180nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024508BDBM50024508(5-[(4-Chloro-phenyl)-fluoro-(4-fluoro-phenyl)-meth...)
Affinity DataEC50:  195nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 9460BDBM9460(3-(4-aminophenyl)-3-ethyl-piperidine-2,6-dione | C...)
Affinity DataEC50:  260nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024483BDBM50024483((4-Nitro-phenyl)-phenyl-pyrimidin-5-yl-methanol | ...)
Affinity DataEC50:  270nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024490BDBM50024490(5-[Chloro-bis-(4-chloro-phenyl)-methyl]-pyrimidine...)
Affinity DataEC50:  275nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024519BDBM50024519((4-Chloro-phenyl)-(3-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  350nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 31772BDBM31772(Brentan | 1-[2-(2,4-dichlorobenzyl)oxy-2-(2,4-dich...)
Affinity DataEC50:  400nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024495BDBM50024495(Pyrimidin-5-yl-di-p-tolyl-methanol | CHEMBL283085)
Affinity DataEC50:  410nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024488BDBM50024488(Bis-(4-fluoro-phenyl)-pyrimidin-5-yl-methanol | CH...)
Affinity DataEC50:  530nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024480BDBM50024480((3,4-Dichloro-phenyl)-phenyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  1.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024485BDBM50024485(5-[1,1-Bis-(4-chloro-phenyl)-2-phenyl-ethyl]-pyrim...)
Affinity DataEC50:  1.01E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024521BDBM50024521((4-Fluoro-phenyl)-(3-fluoro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  1.15E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024491BDBM50024491(5-[(2-Chloro-phenyl)-fluoro-(4-fluoro-phenyl)-meth...)
Affinity DataEC50:  1.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024505BDBM50024505((3,4-Dimethyl-phenyl)-(4-methoxy-3-methyl-phenyl)-...)
Affinity DataEC50:  1.40E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024525BDBM50024525((4-Chloro-phenyl)-(3-fluoro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  1.65E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024482BDBM50024482(Phenyl-pyrimidin-5-yl-(4-trifluoromethyl-phenyl)-m...)
Affinity DataEC50:  1.95E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024510BDBM50024510(Cyclopentyl-cyclopropyl-pyrimidin-5-yl-methanol | ...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024512BDBM50024512(Cyclohexyl-pyrimidin-5-yl-p-tolyl-methanol | CHEMB...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024506BDBM50024506((4-Chloro-phenyl)-phenyl-pyrimidin-5-yl-methanol |...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024487BDBM50024487(1-(4-Chloro-phenyl)-2-methyl-1-pyrimidin-5-yl-prop...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024514BDBM50024514(Cyclopropyl-(4-methoxy-phenyl)-pyrimidin-5-yl-meth...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024486BDBM50024486(Bis-(4-chloro-phenyl)-(1-oxy-pyrimidin-5-yl)-metha...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024509BDBM50024509(Cyclobutyl-(4-methoxy-phenyl)-pyrimidin-5-yl-metha...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024484BDBM50024484(5-[1,1,2-Tris-(4-chloro-phenyl)-ethyl]-pyrimidine ...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024492BDBM50024492(Diphenyl-pyrimidin-5-yl-methanol | CHEMBL29670)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024523BDBM50024523((4-Methoxy-phenyl)-phenyl-pyrimidin-5-yl-methanol ...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024502BDBM50024502(1-(4-Methoxy-phenyl)-2,2-dimethyl-1-pyrimidin-5-yl...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024503BDBM50024503(Cyclopropyl-pyrimidin-5-yl-thiophen-2-yl-methanol ...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024500BDBM50024500(Phenyl-pyrimidin-5-yl-thiophen-2-yl-methanol | CHE...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024499BDBM50024499(1-(4-Methoxy-phenyl)-2-methyl-1-pyrimidin-5-yl-but...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024497BDBM50024497(2-Methyl-1-(5-methyl-thiophen-2-yl)-1-pyrimidin-5-...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024496BDBM50024496(Pyrimidin-5-yl-di-thiophen-2-yl-methanol | CHEMBL2...)
Affinity DataEC50: >2.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024494BDBM50024494((4-Fluoro-phenyl)-phenyl-pyrimidin-5-yl-methanol |...)
Affinity DataEC50: >2.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024489BDBM50024489(5-[Bis-(4-chloro-phenyl)-methylene]-1,4,5,6-tetrah...)
Affinity DataEC50:  2.70E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024498BDBM50024498(5-[1,1-Bis-(4-chloro-phenyl)-propyl]-pyrimidine | ...)
Affinity DataEC50:  2.95E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024507BDBM50024507((3,4-Dimethyl-phenyl)-phenyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  3.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024518BDBM50024518((4-Chloro-phenyl)-cyclohexyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  4.00E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024511BDBM50024511((4-Chloro-phenyl)-(2-chloro-phenyl)-pyrimidin-5-yl...)
Affinity DataEC50:  4.10E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024493BDBM50024493(Cyclopropyl-(4-fluoro-phenyl)-pyrimidin-5-yl-metha...)
Affinity DataEC50:  4.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024504BDBM50024504((2-Chloro-4-methoxy-phenyl)-(4-chloro-phenyl)-pyri...)
Affinity DataEC50:  4.30E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024501BDBM50024501((4-Bromo-phenyl)-cyclopropyl-pyrimidin-5-yl-methan...)
Affinity DataEC50:  5.40E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024479BDBM50024479((4-Chloro-phenyl)-cyclopropyl-pyrimidin-5-yl-metha...)
Affinity DataEC50:  5.70E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
TargetAromatase(Rat)
TBA

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50024517BDBM50024517(Cyclooctyl-(4-methoxy-phenyl)-pyrimidin-5-yl-metha...)
Affinity DataEC50:  6.20E+3nMAssay Description:In vitro inhibition of cytochrome P450 19A1 by rat ovarian microsomes incubated with [3H]androstenedione and NADPH-generating system.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2012
Entry Details Article
PubMed
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