Compile Data Set for Download or QSAR
maximum 50k data
Found 6 Enz. Inhib. hit(s) with all data for entry = 50015821
TargetParkinson disease protein 7(Homo sapiens)
Leiden University Medical Center

Curated by ChEMBL
LigandPNGBDBM50589874(JYQ88)
Affinity DataIC50:  130nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PARK7 expressed in Escherichia coli BL21(DE3)Rosetta2 cells using DiFMUAc as substrate preincub...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center

Curated by ChEMBL
LigandPNGBDBM50589875(8RK64)
Affinity DataIC50:  230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-AMC as substrate preincubated with enzyme for 1 hr followed by substrate addition and measured for 1 hr...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center

Curated by ChEMBL
LigandPNGBDBM50589875(8RK64)
Affinity DataIC50:  230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-Rho-Morpholine as substrate preincubated with enzyme for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetParkinson disease protein 7(Homo sapiens)
Leiden University Medical Center

Curated by ChEMBL
LigandPNGBDBM50589874(JYQ88)
Affinity DataIC50:  240nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PARK7 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as reduction in JQ-107-lab...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center

Curated by ChEMBL
LigandPNGBDBM50589874(JYQ88)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-Rho-Morpholine as substrate preincubated with enzyme for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center

Curated by ChEMBL
LigandPNGBDBM50589874(JYQ88)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-AMC as substrate preincubated with enzyme for 1 hr followed by substrate addition and measured for 1 hr...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed