Affinity DataIC50: 130nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PARK7 expressed in Escherichia coli BL21(DE3)Rosetta2 cells using DiFMUAc as substrate preincub...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center
Curated by ChEMBL
Leiden University Medical Center
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-AMC as substrate preincubated with enzyme for 1 hr followed by substrate addition and measured for 1 hr...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center
Curated by ChEMBL
Leiden University Medical Center
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-Rho-Morpholine as substrate preincubated with enzyme for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
Affinity DataIC50: 240nMAssay Description:Inhibition of N-terminal GST-tagged human recombinant PARK7 expressed in Escherichia coli BL21(DE3)Rosetta2 cells assessed as reduction in JQ-107-lab...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center
Curated by ChEMBL
Leiden University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-Rho-Morpholine as substrate preincubated with enzyme for 1 hr followed by substrate addition and measur...More data for this Ligand-Target Pair
TargetUbiquitin carboxyl-terminal hydrolase isozyme L1(Homo sapiens (Human))
Leiden University Medical Center
Curated by ChEMBL
Leiden University Medical Center
Curated by ChEMBL
Affinity DataIC50: 1.11E+4nMAssay Description:Inhibition of UCHL1 (unknown origin) using Ub-AMC as substrate preincubated with enzyme for 1 hr followed by substrate addition and measured for 1 hr...More data for this Ligand-Target Pair