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Found 49 Enz. Inhib. hit(s) with all data for entry = 50015825
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataKi:  9nMAssay Description:Inhibition of human MMP-2 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataKi:  13nMAssay Description:Inhibition of human MMP-8 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  100nMAssay Description:Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColQ1 assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM11859(2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...)
Affinity DataKi:  100nMAssay Description:Inhibition of human MMP-8 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM11859(2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...)
Affinity DataKi:  200nMAssay Description:Inhibition of Clostridium histolyticum CoLH assessed as inhibition constant using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589972(CHEMBL5191074)
Affinity DataKi:  820nMAssay Description:Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColQ1 assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589972(CHEMBL5191074)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of Clostridium histolyticum peptidase unit of ColH assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM11859(2-({[(4-fluorobenzene)sulfonyl]carbamoyl}amino)-3-...)
Affinity DataKi:  2.00E+3nMAssay Description:Inhibition of human MMP-2 assessed as inhibition constant using AcProLeuGly-S-LeuLeuGlyOEt as substrate by spectrophotometer analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase ColA(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  3.40E+3nMAssay Description:Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColA assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCollagenase ColA(Bacillus cereus (strain ATCC 14579 / DSM 31 / CCUG...)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589972(CHEMBL5191074)
Affinity DataKi:  4.70E+3nMAssay Description:Inhibition of Bacillus cereus ATCC 14579 collagenase unit of ColA assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  1.16E+4nMAssay Description:Inhibition of Clostridium histolyticum peptidase unit of ColH assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCollagenase ColG(Clostridium histolyticum)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589972(CHEMBL5191074)
Affinity DataKi:  1.84E+4nMAssay Description:Inhibition of Clostridium histolyticum collagenase unit of ColG assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColG(Clostridium histolyticum)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataKi:  3.10E+4nMAssay Description:Inhibition of Clostridium histolyticum collagenase unit of ColG assessed as inhibition constant incubated for 144 seconds by FRET based assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589974(CHEMBL5186191)
Affinity DataIC50:  10nMAssay Description:Inhibition of Clostridium histolyticum CoLHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50542711(CHEMBL4640494)
Affinity DataIC50:  17nMAssay Description:Inhibition of Clostridium histolyticum CoLHMore data for this Ligand-Target Pair
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589973(CHEMBL5184569)
Affinity DataIC50:  21nMAssay Description:Inhibition of Clostridium histolyticum CoLH using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated for 10 mins by fluorescence spe...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50361374(SCOPARONE)
Affinity DataIC50:  24nMAssay Description:Inhibition of Clostridium histolyticum CoLH using M MOCAcPro-Leu-Gly-Leu-A2pr-(DNP)Ala-Arg-NH2 as substrate incubated for 10 mins by fluorescence spe...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50:  1.20E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589972(CHEMBL5191074)
Affinity DataIC50:  1.60E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589977(CHEMBL5200591)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589978(CHEMBL5192818)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589976(CHEMBL5185345)
Affinity DataIC50:  4.00E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589979(CHEMBL5177477)
Affinity DataIC50:  5.20E+3nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCollagenase ColH(Hathewaya histolytica)
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589975(CHEMBL5179045)
Affinity DataIC50:  7.00E+3nMAssay Description:Inhibition of Clostridium histolyticum CoLHMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589986(CHEMBL5203868)
Affinity DataIC50:  1.01E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589981(CHEMBL5178826)
Affinity DataIC50:  1.05E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589985(CHEMBL5170551)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50:  1.60E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589984(CHEMBL5193278)
Affinity DataIC50:  1.62E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589979(CHEMBL5177477)
Affinity DataIC50:  3.30E+4nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589982(CHEMBL5184903)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetCollagenase ColQ1(Bacillus cereus (strain Q1))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589983(CHEMBL5171722)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of Bacillus cereus collagenase unit of N-terminal His6-tagged ColQ1 expressed in Escherichia coli NiCo21(DE3) cells incubated for 144 seco...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589987(SR 41319B | SR-41319B | Skelid | TILUDRONATE DISOD...)
Affinity DataIC50:  5.00E+4nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589979(CHEMBL5177477)
Affinity DataIC50:  5.30E+4nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589979(CHEMBL5177477)
Affinity DataIC50:  7.90E+4nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589987(SR 41319B | SR-41319B | Skelid | TILUDRONATE DISOD...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589981(CHEMBL5178826)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589987(SR 41319B | SR-41319B | Skelid | TILUDRONATE DISOD...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589981(CHEMBL5178826)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-2More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50247920(Alendronate Sodium | Binosto | Fosamax | G-704650 ...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589980(CHEMBL5186687)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetStromelysin-1(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589971(CHEMBL5187038)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant MMP-3More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Helmholtz Center For Infection Research (Hzi)

Curated by ChEMBL
LigandPNGBDBM50589981(CHEMBL5178826)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant N-terminal his6-tagged MMP-1 expressed in HEK293 cells by microplate reader analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed