Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50015827
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataIC50: 1.20nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50200182((1S,3R,5Z,7E)-9,10-secocholesta-5,7,10(19)-triene-...)
Affinity DataEC50:  3nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589996(CHEMBL5182683)
Affinity DataEC50:  3nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
Target1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589995(CHEMBL5175578)
Affinity DataEC50:  5.60nMAssay Description:Induction of CYP24A1 (unknown orgin) transcriptional activity trasfected in human MCF7 cells incuabted for 48 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589996(CHEMBL5182683)
Affinity DataIC50: 15.7nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed
TargetVitamin D3 receptor(Human)
University of Santiago De Compostela

Curated by ChEMBL
LigandPNGBDBM50589995(CHEMBL5175578)
Affinity DataIC50: 27.3nMAssay Description:Competitive binding affinity to His-tagged human VDR LBD (156 to 453 residues) expressed in Escherichia coli BL23 (DE3) cells in presence of 1,25D3 b...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMed