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Found 18 Enz. Inhib. hit(s) with all data for entry = 50017440
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094465(CHEMBL3590106 | US10525036, Example BVD-523 | US10...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity to ERK2 (unknown origin) measured after 20 mins in presence of [gamma33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(LY-3214996 | LY3214996 | Ly 3214996 | Ly3214996 | ...)
Affinity DataKi:  0.0640nMAssay Description:Binding affinity to ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094465(CHEMBL3590106 | US10525036, Example BVD-523 | US10...)
Affinity DataKi: <0.300nMAssay Description:Binding affinity to ERK1 (unknown origin) measured after 20 mins in presence of [gamma33P]ATP by scintillation counter analysisMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(LY-3214996 | LY3214996 | Ly 3214996 | Ly3214996 | ...)
Affinity DataKi:  0.650nMAssay Description:Binding affinity to ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Rattus norvegicus (rat))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50526695(BI-78D3 | CHEMBL508280)
Affinity DataKi:  2.30E+3nMAssay Description:Binding affinity to rat full-length ERK2 using FQRKTLQRRNLKGLNLNL-XXX-TGPLSPGPF peptide as substrate in presence of [gamma33P]ATP by scintillation co...More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094464(CHEMBL3590107 | US10525036, Example SCH772984 | US...)
Affinity DataIC50:  1nMAssay Description:Inhibition of ERK2 (unknown origin) incubated for 45 mins in presence of ATP by IMAP assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601920(ASN007 | Asn007 | Asn007 rd)
Affinity DataIC50:  2nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601920(ASN007 | Asn007 | Asn007 rd)
Affinity DataIC50:  2nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50094464(CHEMBL3590107 | US10525036, Example SCH772984 | US...)
Affinity DataIC50:  4nMAssay Description:Inhibition of ERK1 (unknown origin) incubated for 45 mins in presence of ATP by IMAP assayMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(LY-3214996 | LY3214996 | Ly 3214996 | Ly3214996 | ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601918(LY-3214996 | LY3214996 | Ly 3214996 | Ly3214996 | ...)
Affinity DataIC50:  5nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM351000(US9796700, Compound I-90)
Affinity DataIC50:  10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM318045(US10301317, Example 1 | US9624228, Example 1)
Affinity DataIC50:  10nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM351000(US9796700, Compound I-90)
Affinity DataIC50:  10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 3(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM318045(US10301317, Example 1 | US9624228, Example 1)
Affinity DataIC50:  10nMAssay Description:Inhibition of ERK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601919(CHEMBL5180742)
Affinity DataIC50:  500nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601917(CHEMBL5180873)
Affinity DataIC50:  9.90E+3nMAssay Description:Inhibition of ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Southwest Jiaotong University

Curated by ChEMBL
LigandPNGBDBM50601917(CHEMBL5180873)
Affinity DataKd:  380nMAssay Description:Binding affinity to ERK2 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed