Compile Data Set for Download or QSAR
maximum 50k data
Found 54 Enz. Inhib. hit(s) with all data for entry = 50018068
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)
Affinity DataKi:  19nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM171350(1-(2-((1R,3S,5R)-3-((6-Bromopyridin-2-yl)carbamoyl...)
Affinity DataIC50:  6nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474788(US10849883, Compound 208a | US11559515, Compound 2...)
Affinity DataIC50:  27nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474805(US10849883, Compound 237a | US11559515, Compound 2...)
Affinity DataIC50:  28nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474860(US10849883, Compound 278a | US11559515, Compound 2...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM171272(1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474819(US10849883, Compound 246a | US11559515, Compound 2...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474803(US10849883, Compound 235b | US11559515, Compound 2...)
Affinity DataIC50:  34nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)
Affinity DataIC50:  37nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474910(US10849883, Compound 330b | US11559515, Compound 3...)
Affinity DataIC50:  54nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607452(CHEMBL5218654)
Affinity DataIC50:  67nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474933(US10849883, Compound 353b | US11559515, Compound 3...)
Affinity DataIC50:  77nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607459(CHEMBL5220843)
Affinity DataIC50:  84nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474837(US10849883, Compound 263a | US11559515, Compound 2...)
Affinity DataIC50:  87nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474932(US10849883, Compound 352b | US11559515, Compound 3...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474806(US10849883, Compound 238a | US11559515, Compound 2...)
Affinity DataIC50:  89nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474778(US10849883, Compound 207g)
Affinity DataIC50:  90nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474607(US10849883, Compound 36b | US11559515, Compound 36...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474609(US10849883, Compound 38b | US11559515, Compound 38...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474625(US10849883, Compound 53b | US11559515, Compound 53...)
Affinity DataIC50:  100nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474619(US10849883, Compound 48b | US11559515, Compound 48...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474590(US10849883, Compound 19d | US11559515, Compound 19...)
Affinity DataIC50:  120nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474581(US10849883, Compound 10c | US11559515, Compound 10...)
Affinity DataIC50:  130nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474804(US10849883, Compound 236b | US11559515, Compound 2...)
Affinity DataIC50:  160nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607458(CHEMBL5219728)
Affinity DataIC50:  160nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474856(US10849883, Compound 287a | US11559515, Compound 2...)
Affinity DataIC50:  190nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474915(US10849883, Compound 335b | US11559515, Compound 3...)
Affinity DataIC50:  230nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474642(US10849883, Compound 69d | US11559515, Compound 69...)
Affinity DataIC50:  410nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474808(US10849883, Compound 198a | US11559515, Compound 1...)
Affinity DataIC50:  520nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607453(CHEMBL5220503)
Affinity DataIC50:  600nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474708(US10849883, Compound 132g)
Affinity DataIC50:  650nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474633(US10849883, Compound 61b | US11559515, Compound 61...)
Affinity DataIC50:  690nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474606(US10849883, Compound 35d | US11559515, Compound 35...)
Affinity DataIC50:  880nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474613(US10849883, Compound 42b | US11559515, Compound 42...)
Affinity DataIC50:  900nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607457(CHEMBL5220172)
Affinity DataIC50:  1.10E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474615(US10849883, Compound 44f | US11559515, Compound 44...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474649(US10849883, Compound 76b | US11559515, Compound 76...)
Affinity DataIC50:  1.50E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607456(CHEMBL5218912)
Affinity DataIC50:  1.90E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474587(US10849883, Compound 16d | US11559515, Compound 16...)
Affinity DataIC50:  3.00E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607446(CHEMBL5218908)
Affinity DataIC50:  3.40E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474659(US10849883, Compound 85b | US11559515, Compound 85...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607455(CHEMBL5219504)
Affinity DataIC50:  5.30E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM474650(US10849883, Compound 77b | US11559515, Compound 77...)
Affinity DataIC50:  9.50E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607454(CHEMBL5220368)
Affinity DataIC50:  1.30E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM203865(Methyl (S)-2-((2-((3-(trifluoromethoxy)phenyl)carb...)
Affinity DataIC50:  1.40E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607460(CHEMBL5221126)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607450(CHEMBL5221059)
Affinity DataIC50:  2.30E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607451(CHEMBL5218913)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607444(CHEMBL5220109)
Affinity DataIC50:  3.50E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetComplement factor D(Homo sapiens (Human))
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50607445(CHEMBL5221048)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
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