Compile Data Set for Download or QSAR
Report error Found 54 Enz. Inhib. hit(s) with all data for entry = 50018068
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 171350BDBM171350(1-(2-((1R,3S,5R)-3-((6-Bromopyridin-2-yl)carbamoyl...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474862BDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)
Affinity DataKi:  19nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474788BDBM474788(US10849883, Compound 208a | US11559515, Compound 2...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474805BDBM474805(US10849883, Compound 237a | US11559515, Compound 2...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 171272BDBM171272(1-(2-((1R,3S,5R)-3-(((R)-1-(3-Chloro-2-fluoropheny...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474860BDBM474860(US10849883, Compound 278a | US11559515, Compound 2...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474803BDBM474803(US10849883, Compound 235b | US11559515, Compound 2...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474819BDBM474819(US10849883, Compound 246a | US11559515, Compound 2...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474862BDBM474862(US10849883, Compound 279a | US11559515, Compound 2...)
Affinity DataIC50: 37nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474910BDBM474910(US10849883, Compound 330b | US11559515, Compound 3...)
Affinity DataIC50: 54nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607452BDBM50607452(CHEMBL5218654)
Affinity DataIC50: 67nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474933BDBM474933(US10849883, Compound 353b | US11559515, Compound 3...)
Affinity DataIC50: 77nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607459BDBM50607459(CHEMBL5220843)
Affinity DataIC50: 84nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474837BDBM474837(US10849883, Compound 263a | US11559515, Compound 2...)
Affinity DataIC50: 87nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474806BDBM474806(US10849883, Compound 238a | US11559515, Compound 2...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474932BDBM474932(US10849883, Compound 352b | US11559515, Compound 3...)
Affinity DataIC50: 89nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474778BDBM474778(US10849883, Compound 207g)
Affinity DataIC50: 90nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474607BDBM474607(US10849883, Compound 36b | US11559515, Compound 36...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474625BDBM474625(US10849883, Compound 53b | US11559515, Compound 53...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474609BDBM474609(US10849883, Compound 38b | US11559515, Compound 38...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474590BDBM474590(US10849883, Compound 19d | US11559515, Compound 19...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474619BDBM474619(US10849883, Compound 48b | US11559515, Compound 48...)
Affinity DataIC50: 120nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474581BDBM474581(US10849883, Compound 10c | US11559515, Compound 10...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474804BDBM474804(US10849883, Compound 236b | US11559515, Compound 2...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607458BDBM50607458(CHEMBL5219728)
Affinity DataIC50: 160nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474856BDBM474856(US10849883, Compound 287a | US11559515, Compound 2...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474915BDBM474915(US10849883, Compound 335b | US11559515, Compound 3...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474642BDBM474642(US10849883, Compound 69d | US11559515, Compound 69...)
Affinity DataIC50: 410nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474808BDBM474808(US10849883, Compound 198a | US11559515, Compound 1...)
Affinity DataIC50: 520nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607453BDBM50607453(CHEMBL5220503)
Affinity DataIC50: 600nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474708BDBM474708(US10849883, Compound 132g)
Affinity DataIC50: 650nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474633BDBM474633(US10849883, Compound 61b | US11559515, Compound 61...)
Affinity DataIC50: 690nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474606BDBM474606(US10849883, Compound 35d | US11559515, Compound 35...)
Affinity DataIC50: 880nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474613BDBM474613(US10849883, Compound 42b | US11559515, Compound 42...)
Affinity DataIC50: 900nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607457BDBM50607457(CHEMBL5220172)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474615BDBM474615(US10849883, Compound 44f | US11559515, Compound 44...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474649BDBM474649(US10849883, Compound 76b | US11559515, Compound 76...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607456BDBM50607456(CHEMBL5218912)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474587BDBM474587(US10849883, Compound 16d | US11559515, Compound 16...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607446BDBM50607446(CHEMBL5218908)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474659BDBM474659(US10849883, Compound 85b | US11559515, Compound 85...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607455BDBM50607455(CHEMBL5219504)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 474650BDBM474650(US10849883, Compound 77b | US11559515, Compound 77...)
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607454BDBM50607454(CHEMBL5220368)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 203865BDBM203865(Methyl (S)-2-((2-((3-(trifluoromethoxy)phenyl)carb...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607460BDBM50607460(CHEMBL5221126)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607450BDBM50607450(CHEMBL5221059)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607451BDBM50607451(CHEMBL5218913)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607444BDBM50607444(CHEMBL5220109)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetComplement factor D(Human)
Biocryst Pharmaceuticals

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50607445BDBM50607445(CHEMBL5221048)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human complement factor D using Z-L-Lys-SBzl hydrochloride as substrate preincubated for 15 mins followed by substrate addition and mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
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