Found 37 Enz. Inhib. hit(s) with all data for entry = 50016583 TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.850nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 0.980nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.10nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.30nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.40nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.60nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 1.90nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.30nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 2.90nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.10nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.20nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.80nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 5.90nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 9.60nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 14nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 15nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 16nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 29nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 32nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inhibition of JAK1/JAK3 in CD3+ T cells (unknown origin) assessed as reduction in IL-6 stimulated STAT3 phosphorylation incubated for 1.5 hrs by HTRF...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 39nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
Affinity DataIC50: 41nMAssay Description:Inhibition of JAK1/JAK3 in CD3+ T cells (unknown origin) assessed as reduction in IL-2 stimulated STAT5 phosphorylation incubated for 1.5 hrs by HTRF...More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 58nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 67nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 129nMAssay Description:Inhibition of TYK2 in human Jurkat cells assessed as reduction in IFNalpha induced STAT3 phosphorylation incubated for 24 hrs by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of TYK2 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JAK2 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JAK1 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of JAK3 JH1 (unknown origin) using ULight -poly GT as substrate in presence of ATP incubated for 120 mins by TR-FRET assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of JAK2 in platelet cells (unknown origin) assessed as reduction in EPO stimulated STAT3 phosphorylation by HTRF assayMore data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Nanjing University Of Science And Technology
Curated by ChEMBL
Nanjing University Of Science And Technology
Curated by ChEMBL
Affinity DataKd: <0.0170nMAssay Description:Binding affinity to T7-tagged TYK2 JH2 (unknown origin) expressed in Escherichia coli BL21 cells incubated for 1 hr by qPCR analysisMore data for this Ligand-Target Pair
