Affinity DataIC50: 0.350nMAssay Description:Displacement of [125I]Sar1,I1e8-AII from AT1 receptor in rabbit aorta membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant wild-type BTK (unknown origin) assessed as inhibition of substrate phosphorylation using peptide substrate in presence of A...More data for this Ligand-Target Pair
Affinity DataIC50: 0.550nMAssay Description:Displacement of [125I]Sar1,I1e8-AII from AT1 receptor in rabbit aorta membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inhibition of plasma kallikrein (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 1.80nMAssay Description:Inhibition of BTK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 2.70nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human DPP4 expressed in Silkworm baculovirus system preincubated for 30 mins followed by substrate addition and measured after 20 mins ...More data for this Ligand-Target Pair
Affinity DataIC50: 4nMAssay Description:Inhibition of JAK1 (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tianjin University
Curated by ChEMBL
Tianjin University
Curated by ChEMBL
Affinity DataIC50: 5.20nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 6.60nMAssay Description:Inhibition of JAK2 (unknown origin)More data for this Ligand-Target Pair
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tianjin University
Curated by ChEMBL
Tianjin University
Curated by ChEMBL
Affinity DataIC50: 8.30nMAssay Description:Inhibition of PDE5 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Inhibition of CB1 receptor (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 26nMAssay Description:Inhibition of full length human AR stably expressed in human HEK293 cells assessed as luciferase activity incubated for 24 hrs by microplate luminome...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Inhibition of ALK (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Displacement of [125I]Sar1,I1e8-AII from AT1 receptor in rabbit aorta membraneMore data for this Ligand-Target Pair
Affinity DataIC50: 105nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Tianjin University
Curated by ChEMBL
Tianjin University
Curated by ChEMBL
Affinity DataKd: 6.20nMAssay Description:Inhibition of human PI3K-delta by HTRF assayMore data for this Ligand-Target Pair