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Found 6 Enz. Inhib. hit(s) with all data for entry = 50015860
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590141(CHEMBL5176133)
Affinity DataIC50:  23nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590140(CHEMBL5202162)
Affinity DataIC50:  176nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590141(CHEMBL5176133)
Affinity DataIC50:  1.00E+4nMAssay Description:Displacement of [3H]-epibatidine from recombinant Lymnaea stagnalis Acetylcholine-binding protein by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetAcetylcholine-binding protein(Lymnaea stagnalis)
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590140(CHEMBL5202162)
Affinity DataIC50:  2.00E+4nMAssay Description:Displacement of [3H]-epibatidine from recombinant Lymnaea stagnalis Acetylcholine-binding protein by radioligand binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590143(CHEMBL5180704)
Affinity DataIC50:  3.50E+4nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Homo sapiens (Human))
The University Of Queensland

Curated by ChEMBL
LigandPNGBDBM50590142(CHEMBL5170487)
Affinity DataIC50:  4.60E+4nMAssay Description:Negative allosteric modulation activity at alpha7 nAChR in human SH-SY5Y cells assessed as inhibition of choline induced intracellular calcium by FLI...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed