Compile Data Set for Download or QSAR
Report error Found 29 Enz. Inhib. hit(s) with all data for entry = 50017488
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 14390BDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50033312BDBM50033312(Urapidil-5-methyl | CHEMBL539806 | Benzyl-(6-chlor...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human platelet PDE5More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50518228BDBM50518228(CHEMBL4445920)
Affinity DataIC50: 100nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602260BDBM50602260(CHEMBL5175706)
Affinity DataIC50: 150nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602263BDBM50602263(CHEMBL5178863)
Affinity DataIC50: 220nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602240BDBM50602240(CHEMBL5194921)
Affinity DataIC50: 290nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602247BDBM50602247(CHEMBL5187496)
Affinity DataIC50: 360nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602245BDBM50602245(CHEMBL5194783)
Affinity DataIC50: 410nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602246BDBM50602246(CHEMBL5184989)
Affinity DataIC50: 430nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602243BDBM50602243(CHEMBL5203939)
Affinity DataIC50: 490nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602241BDBM50602241(CHEMBL5186856)
Affinity DataIC50: 500nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602242BDBM50602242(CHEMBL5195499)
Affinity DataIC50: 520nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602244BDBM50602244(CHEMBL5191104)
Affinity DataIC50: 600nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602259BDBM50602259(CHEMBL5200202)
Affinity DataIC50: 1.03E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602248BDBM50602248(CHEMBL5199387)
Affinity DataIC50: 1.44E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602239BDBM50602239(CHEMBL5188731)
Affinity DataIC50: 1.64E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602258BDBM50602258(CHEMBL5177893)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602264BDBM50602264(CHEMBL5195434)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602250BDBM50602250(CHEMBL5171693)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602256BDBM50602256(CHEMBL5183230)
Affinity DataIC50: 4.46E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602249BDBM50602249(CHEMBL5208363)
Affinity DataIC50: 5.23E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602262BDBM50602262(CHEMBL5193660)
Affinity DataIC50: 5.28E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602261BDBM50602261(CHEMBL5196307)
Affinity DataIC50: 9.39E+3nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602253BDBM50602253(CHEMBL5183757)
Affinity DataIC50: 1.89E+4nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602257BDBM50602257(CHEMBL5206939)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602255BDBM50602255(CHEMBL5195857)
Affinity DataIC50: 2.85E+4nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602254BDBM50602254(CHEMBL5193806)
Affinity DataIC50: 3.33E+4nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602251BDBM50602251(CHEMBL5188011)
Affinity DataIC50: 3.84E+4nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
King Mongkut'S Institute of Technology

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 50602252BDBM50602252(CHEMBL5200266)
Affinity DataIC50: 4.32E+4nMAssay Description:Inhibition of human PDE5 using [3H]cGMP as substrate incubated for 10 mins by liquid scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMed