Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50019957
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625075(CHEMBL5417346)
Affinity DataIC50: 0.100nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625080(CHEMBL5433692)
Affinity DataIC50: 0.140nMAssay Description:Inhibition of AChE in human ErythrocyteMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataIC50: 0.200nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625074(CHEMBL5440753)
Affinity DataIC50: 0.400nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625078(CHEMBL5426103)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625073(CHEMBL5434553)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625077(CHEMBL5417632)
Affinity DataIC50: 1nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625076(CHEMBL5418455)
Affinity DataIC50: 2nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625072(CHEMBL5396497)
Affinity DataIC50: 7nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625080(CHEMBL5433692)
Affinity DataKi:  22nMAssay Description:Inhibition of human AChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625080(CHEMBL5433692)
Affinity DataKi:  140nMAssay Description:Reversible inhibition of human AChE assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataKi:  150nMAssay Description:Mixed competitive inhibition of human AChE assessed as inhibition of constant by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50313079(Mestinon | Regonol | Pyridostigmine | CHEMBL812 | ...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human AChE using acetylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Per...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetAcetylcholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataKi:  430nMAssay Description:Mixed uncompetitive inhibition of human AChE assessed as inhibition of constant by cornish-bowden plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50313079(Mestinon | Regonol | Pyridostigmine | CHEMBL812 | ...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625080(CHEMBL5433692)
Affinity DataKi:  1.77E+3nMAssay Description:Reversible inhibition of human BChE assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625080(CHEMBL5433692)
Affinity DataKi:  3.17E+3nMAssay Description:Inhibition of human BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625072(CHEMBL5396497)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625075(CHEMBL5417346)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625080(CHEMBL5433692)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human plasma BChEMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625073(CHEMBL5434553)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataKi:  3.50E+4nMAssay Description:Mixed competitive inhibition of human BChE assessed as inhibition of constant by Dixon plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625074(CHEMBL5440753)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625079(CHEMBL5419243)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625078(CHEMBL5426103)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625077(CHEMBL5417632)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetCholinesterase(Human)
Frc Kazan Scientific Center of Ras

Curated by ChEMBL
LigandPNGBDBM50625076(CHEMBL5418455)
Affinity DataIC50: 4.40E+5nMAssay Description:Inhibition of human BChE using butyrylthiocholine as substrate preincubated for 5 mins followed by substrate addition and measured after 2 mins by Pe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed